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[一名接触石蜡基矿物油的工人发生横纹肌溶解症。与闭塞性细支气管炎和机化性肺炎(BOOP)的不寻常关联]

[Rhabdomyolysis in a worker exposed to paraffinic mineral oils. Unusual association with bronchiolitis obliterans and organizing pneumonia (BOOP)].

作者信息

Ragno G, Brunetti G, Scafa F, Scelsi M, Martellosio V, Candura S M

机构信息

Scuola di Specializzazione in Medicina del Lavoro, Università degli Studi di Pavia.

出版信息

G Ital Med Lav Ergon. 2007 Jul-Sep;29(3 Suppl):437-8.

Abstract

We describe a 29-year-old worker; exposed to metal dust, sawdust and paraffinic mineral oils in a factory producing accessories for leather articles and clothing, who came to observation with fever (39 degrees C), chest pain and marked increase of muscular enzymes. Chest computed tomography showed two areas of lung consolidation, that subsequently appeared enlarged with central escavation. Lung biopsy lead to the diagnosis of BOOP. The case has been reported to the judicial and workers' compensation authorities as probable occupational toxic myopathy. Indeed, exposure to paraffinic mineral oils is a known, though unusual, cause of rhabdomyolysis. The association with BOOP has never been previously described.

摘要

我们描述了一名29岁的工人,他在一家生产皮革制品和服装配饰的工厂中接触金属粉尘、锯末和石蜡矿物油,因发热(39摄氏度)、胸痛和肌肉酶显著升高前来就诊。胸部计算机断层扫描显示肺部有两个实变区域,随后这些区域出现增大并伴有中央空洞形成。肺活检确诊为闭塞性细支气管炎伴机化性肺炎(BOOP)。该病例已作为可能的职业性中毒性肌病报告给司法和工人赔偿当局。事实上,接触石蜡矿物油是横纹肌溶解症的一个已知但不常见的病因。此前从未有过与BOOP相关的描述。

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