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[利用医学监测报告和暴露登记数据对木工上下呼吸道疾病患病率的研究]

[Study on prevalence of upper and lower airways disorders in woodworkers, using data from medical surveillance reports and exposure registers].

作者信息

Veneri L, Caso M A, Ravaioli M, Albonetti A, Ghini P, Mazzavillani M, Valentini M G

机构信息

Dipartimento di Sanità Pubblica, Unità Operativa Prevenzione e Sicurezza negli Ambienti di Lavoro, AUSL Forlì, via della Rocca 19, 47100 Forlì, Italy.

出版信息

G Ital Med Lav Ergon. 2007 Jul-Sep;29(3 Suppl):833-5.

Abstract

OBJECTIVES

To evaluate correlations between exposure to wood dust, upper airways symptoms and lung function.

METHODS

We have analysed medical surveillance reports of 197 woodworkers with a median wood dust TWA exposure of 2.1 mg/m3. Every worker was examined by an otorhinolaryngologist and had a spirometric test. The results have been analysed with logistic regression to correlate prevalence of symptoms and spirometric data with occupational exposure to wood dust, length of service, regular use of respiratory protection and smoking habits.

RESULTS

Epistaxis (prevalence: 10.1%) correlates with no smoking habits (OR = 6.4; p = 0.01); subacute or chronic rhinitis (prevalence: 41.6%) correlates with exposure to wood dust (O = 1.37; p = 0.01) and no use of respirstory protection (OR = 1.68; p = 0.09); subacute or chronic pharyngitis (prevalence: 17.2%) has a weak but significant correlation with length of service (OR = 1.03; p = 0.05); decrease in FEF25-75 (prevalence: 19.8%) correlates with no use of respiratory protection (OR = 2.56; p = 0.02) and exposure to wood dust (OR = 1.29; p = 0.09); pathologic decrease of VC (prevalence: 5.1%) correlates with exposure to wood dust (OR = 1.69; p = 0.05).

CONCLUSIONS

this study seems to confirm that chronic irritation of upper and lower respiratory tract are caused by exposure to wood dust below the european 8 hours exposure legal limit of 5 mg/m3.

摘要

目的

评估接触木尘、上呼吸道症状与肺功能之间的相关性。

方法

我们分析了197名木工的医学监测报告,这些木工的木尘时间加权平均暴露量中位数为2.1毫克/立方米。每位工人都接受了耳鼻喉科医生的检查并进行了肺活量测定。结果通过逻辑回归进行分析,以将症状患病率和肺活量测定数据与职业性接触木尘、服务年限、是否经常使用呼吸防护用品以及吸烟习惯相关联。

结果

鼻出血(患病率:10.1%)与不吸烟习惯相关(比值比=6.4;p=0.01);亚急性或慢性鼻炎(患病率:41.6%)与接触木尘(比值比=1.37;p=0.01)以及不使用呼吸防护用品相关(比值比=1.68;p=0.09);亚急性或慢性咽炎(患病率:17.2%)与服务年限呈弱但显著的相关性(比值比=1.03;p=0.05);用力呼气流量25%-75%下降(患病率:19.8%)与不使用呼吸防护用品(比值比=2.56;p=0.02)以及接触木尘相关(比值比=1.29;p=0.09);肺活量病理性下降(患病率:5.1%)与接触木尘相关(比值比=1.69;p=0.05)。

结论

本研究似乎证实,低于欧洲8小时暴露法定限值5毫克/立方米的木尘接触会导致上、下呼吸道的慢性刺激。

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