Kupelian Varant, Link Carol L, Rosen Raymond C, McKinlay John B
New England Research Institutes, Watertown, MA, USA.
J Sex Med. 2008 Jun;5(6):1325-33. doi: 10.1111/j.1743-6109.2008.00822.x. Epub 2008 Apr 10.
Few population-based studies have assessed variations in the burden of erectile dysfunction (ED) by race/ethnicity.
To estimate prevalence rates of ED by race/ethnicity and determine the contribution of behavioral risk factors, chronic illnesses, and socioeconomic factors to potential race/ethnic differences in ED.
The Boston Area Community Health (BACH) Survey is a study of urologic symptoms in a racially and ethnically diverse population. BACH used a multistage stratified random sample to recruit 2,301 men aged 30-79 years from the city of Boston. Self-reported race/ethnicity was defined as Black, Hispanic, and White. Socioeconomic status (SES) was defined as a combination of education and household income.
ED assessed using the 5-item International Index of Erectile Function (IIEF-5). IIEF-5 scores were used both as a continuous variable and dichotomized as </=16 vs. >/=17.
Overall prevalence of ED (defined as an IIEF-5 score </=16) was 20.7% with higher prevalence observed among both Black men (24.9%) and Hispanic men (25.3%) compared to White men (18.1%). Increased odds of ED were observed for both Black and Hispanic men after adjusting for age, comorbid conditions (cardiovascular disease, diabetes, depression), and behavioral risk factors (smoking, physical activity, alcohol use). After controlling for the effect of SES, the association between race/ethnicity and ED disappeared. In contrast, men in the low SES category had an over two-fold increase in risk of ED (adjusted odds ratio of 2.26, 95% confidence interval 1.39, 3.66).
The increased risk of ED in Black and Hispanic men is associated with differences in SES rather than differences in known risk factors of ED.
很少有基于人群的研究评估过按种族/民族划分的勃起功能障碍(ED)负担差异。
按种族/民族估计ED患病率,并确定行为风险因素、慢性病和社会经济因素对ED潜在种族/民族差异的影响。
波士顿地区社区健康(BACH)调查是一项针对种族和民族多样化人群的泌尿系统症状研究。BACH采用多阶段分层随机抽样,从波士顿市招募了2301名30 - 79岁的男性。自我报告的种族/民族定义为黑人、西班牙裔和白人。社会经济地位(SES)定义为教育程度和家庭收入的综合指标。
使用5项国际勃起功能指数(IIEF - 5)评估ED。IIEF - 5评分既作为连续变量使用,也分为≤16和≥17进行二分法分析。
ED的总体患病率(定义为IIEF - 5评分≤16)为20.7%,与白人男性(18.1%)相比,黑人男性(24.9%)和西班牙裔男性(25.3%)的患病率更高。在调整年龄、合并症(心血管疾病、糖尿病、抑郁症)和行为风险因素(吸烟、体育活动、饮酒)后,黑人男性和西班牙裔男性患ED的几率均增加。在控制了SES的影响后,种族/民族与ED之间的关联消失。相比之下,低SES类别的男性患ED的风险增加了两倍多(调整后的优势比为2.26,95%置信区间为1.39,3.66)。
黑人男性和西班牙裔男性患ED风险增加与SES差异有关,而非与已知的ED风险因素差异有关。