Freitag F M, Cestari T F, Leopoldo L R, Paludo P, Boza J C
J Eur Acad Dermatol Venereol. 2008 Jun;22(6):655-62. doi: 10.1111/j.1468-3083.2007.02472.x. Epub 2008 Apr 10.
Melasma can cause a significant effect on individual emotional well-being. Melasma Quality of Life Scale (MELASQoL) is a specific questionnaire elaborated to assess the burden of melasma on patient's quality of life.
To evaluate the clinical aspects, severity and the influence of melasma on daily living of a sample of Brazilian women.
Cross-sectional study that enrolled 85 women with melasma older than 15 years of age. Trained investigators asked 55 questions to collect epidemiological and clinical data. The disease severity was clinically assessed using Melasma Area and Severity Index (MASI). Patients answered the Portuguese version of 10-item MELASQoL scale without coaching.
The mean +/- SD age was 41.1 +/- 6.8 years, and the mean +/- SD of MELASQoL score was 37.5 +/- 15.2 (median, 35). Patients with previous psychiatric diagnosis had significantly higher MELASQoL scores (mean, 42.8; SD, 13.6) than patients without this antecedent (mean, 35.4; SD, 15.4; P < 0.05). Patients with less than 8 years of school attendance also had significantly higher MELASQoL score (mean, 44; SD, 16.9) than more graduated ones (mean, 34.4; SD, 13.5; P < 0.05). The mean +/- SD MASI was 10.6 +/- 6.6 (median, 10.2). There was no correlation between MASI and MELASQoL.
This study confirms that MELASQoL-BP is easy to administer, adds important information about the impact of melasma on South American women's life and, finally, contributes to building evidence on the validity, reliability and cultural adaptation of the Portuguese language MELASQoL version.
黄褐斑会对个人情绪健康产生重大影响。黄褐斑生活质量量表(MELASQoL)是一份专门设计的问卷,用于评估黄褐斑对患者生活质量的负担。
评估巴西女性样本中黄褐斑的临床特征、严重程度及其对日常生活的影响。
采用横断面研究,纳入85名年龄超过15岁的黄褐斑女性。经过培训的调查人员询问了55个问题,以收集流行病学和临床数据。使用黄褐斑面积和严重程度指数(MASI)对疾病严重程度进行临床评估。患者在没有指导的情况下回答了葡萄牙语版的10项MELASQoL量表。
平均年龄±标准差为41.1±6.8岁,MELASQoL评分的平均±标准差为37.5±15.2(中位数为35)。既往有精神疾病诊断的患者MELASQoL评分(平均42.8;标准差13.6)显著高于无此病史的患者(平均35.4;标准差15.4;P<0.05)。受教育年限少于8年的患者MELASQoL评分(平均44;标准差16.9)也显著高于受教育程度较高的患者(平均34.4;标准差13.5;P<0.05)。平均±标准差的MASI为10.6±6.6(中位数为10.2)。MASI与MELASQoL之间无相关性。
本研究证实,MELASQoL-BP易于实施,增加了有关黄褐斑对南美女性生活影响的重要信息,最终有助于建立葡萄牙语版MELASQoL有效性、可靠性和文化适应性的证据。