Ikino Juliana Kida, Nunes Daniel Holthausen, Silva Vanessa Priscilla Martins da, Fröde Tania Silvia, Sens Mariana Mazzochi
Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
Florianópolis, Florianópolis, SC, Brazil.
An Bras Dermatol. 2015 Mar-Apr;90(2):196-200. doi: 10.1590/abd1806-4841.20152771.
Melasma is a chronic, acquired hyperpigmentation disease on sun-exposed areas of the skin, which affects patients' quality of life.
To assess the impact on the quality of life of women living in Florianópolis, Brazil, through questionnaire (MelasQol), and investigate the clinical aspects and risk factors for melasma, correlating them with the MelasQol scores.
This study was performed on 51 melasma patients cared for at the University Hospital of the Universidade Federal de Santa Catarina. The variables included were: age, gender, age of onset of melasma, Fitzpatrick phototype (I-VI), duration and family history of melasma, onset of melasma during pregnancy, use of hormonal contraceptive, thyroid disorder and distribution of melasma. The MelasQoL questionnaire, validated for Brazilian Portuguese (MelasQoL-BP), was applied.
The mean age was 38.43±6.75 years. All patients were women. The most common Fitzpatrick skin phototypes were III (49.02%) and IV (33.33%). Melasma had a mean age of onset of 29.18±7.05 years and a mean duration of 9.25±6.18 years. The majority of patients did not have familial history of melasma (50.98%). Melasma onset was associated with pregnancy (45.10%). The MelasQoL-BP analysis revealed significant emotional impact on patients, such as feeling bothered (94.11%), frustrated and embarrassed (64.71%), and depressed (52.94%) about their skin appearance, as well as unattractive (78.43%). No social impact was observed (P>0.05).
Melasma has a strong emotional impact on quality of life, resulting especially from feelings about skin appearance.
黄褐斑是一种发生于皮肤暴露部位的慢性获得性色素沉着疾病，会影响患者的生活质量。
通过问卷调查（黄褐斑生活质量问卷，MelasQol）评估巴西弗洛里亚诺波利斯市女性的生活质量，并调查黄褐斑的临床特征和危险因素，将其与MelasQol评分相关联。
本研究对51例在圣卡塔琳娜联邦大学大学医院接受治疗的黄褐斑患者进行。纳入的变量包括：年龄、性别、黄褐斑发病年龄、菲茨帕特里克皮肤分型（I - VI型）、黄褐斑病程及家族史、孕期黄褐斑发病情况、激素避孕药使用情况、甲状腺疾病及黄褐斑分布。应用经巴西葡萄牙语验证的MelasQoL问卷（MelasQoL - BP）。
平均年龄为38.43±6.75岁。所有患者均为女性。最常见的菲茨帕特里克皮肤分型为III型（49.02%）和IV型（33.33%）。黄褐斑的平均发病年龄为29.18±7.05岁，平均病程为9.25±6.18年。大多数患者无黄褐斑家族史（50.98%）。黄褐斑发病与妊娠相关（45.10%）。MelasQoL - BP分析显示，患者在情绪方面受到显著影响，例如对自己的皮肤外观感到困扰（94.11%）、沮丧和尴尬（64.71%）、抑郁（52.94%），以及觉得自己没有吸引力（78.43%）。未观察到社会方面的影响（P>0.05）。
黄褐斑对生活质量有强烈的情绪影响，尤其是对皮肤外观的感受。
