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社会经济劣势与急性冠脉事件:一项时空分析

Socioeconomic disadvantage and acute coronary events: a spatiotemporal analysis.

作者信息

Beard John R, Earnest Arul, Morgan Geoff, Chan Hsien, Summerhayes Richard, Dunn Therese M, Tomaska Nola A, Ryan Louise

机构信息

Center for Urban Epidemiologic Studies, New York Academy of Medicine, New York, NY 10029, USA.

出版信息

Epidemiology. 2008 May;19(3):485-92. doi: 10.1097/EDE.0b013e3181656d7f.

Abstract

BACKGROUND

The associations between socioeconomic disadvantage and ischemic heart disease are not well understood. We explore the relationship between socioeconomic factors and acute coronary events using spatiotemporal analysis.

METHODS

We studied all deaths from acute myocardial infarction and hospital admissions for acute coronary syndrome and related revascularization procedures for the state of New South Wales, Australia, from 1996 through 2002. We used conditional autoregressive models to describe how characteristics of subjects' place of residence (socioeconomic disadvantage, proportion of the population of indigenous background, and metropolitan versus nonmetropolitan area) influenced admissions and mortality.

RESULTS

There were 32,534 deaths due to acute myocardial infarction and 129,045 admissions for acute coronary syndrome. We found a relationship between increasing socioeconomic disadvantage and mortality (unadjusted relative risk for highest quartile of disadvantage relative to lowest = 1.40; 95% confidence interval = 1.27-1.54) as well as admissions (1.41; 1.28-1.55). After accounting for admission rates, socioeconomic disadvantage was associated with lower rates of angiography (0.75; 0.63-0.88) and interventional angiography (0.70; 0.56-0.85). After adjusting for socioeconomic disadvantage, areas with higher proportions of the population identified as indigenous had higher rates of admission and mortality, while residency in the state capital was associated with higher admission rates and more interventional angiography. After accounting for admission rates, the association of socioeconomic disadvantage with mortality was reduced.

CONCLUSIONS

Socioeconomic disadvantage increases both the risk of acute coronary syndrome and related mortality. A contributing factor appears to be a reduced chance of receiving appropriate care. Regions with a higher proportion of indigenous residents show risk beyond the effects of general socioeconomic disadvantage, while residents of metropolitan communities had increased utilization of more recent interventions.

摘要

背景

社会经济劣势与缺血性心脏病之间的关联尚未得到充分理解。我们使用时空分析来探究社会经济因素与急性冠状动脉事件之间的关系。

方法

我们研究了1996年至2002年澳大利亚新南威尔士州所有因急性心肌梗死死亡以及因急性冠状动脉综合征和相关血运重建手术住院的病例。我们使用条件自回归模型来描述受试者居住地点的特征(社会经济劣势、原住民背景人口比例以及大城市与非大城市地区)如何影响住院率和死亡率。

结果

有32534例因急性心肌梗死死亡,129045例因急性冠状动脉综合征住院。我们发现社会经济劣势增加与死亡率(劣势最高四分位数相对于最低四分位数的未调整相对风险=1.40;95%置信区间=1.27 - 1.54)以及住院率(1.41;1.28 - 1.55)之间存在关联。在考虑住院率后,社会经济劣势与血管造影率较低(0.75;0.63 - 0.88)和介入性血管造影率较低(0.70;0.56 - .85)相关。在调整社会经济劣势后,被认定为原住民人口比例较高的地区住院率和死亡率较高,而居住在州首府与较高的住院率和更多的介入性血管造影相关。在考虑住院率后,社会经济劣势与死亡率之间的关联有所减弱。

结论

社会经济劣势会增加急性冠状动脉综合征风险和相关死亡率。一个促成因素似乎是接受适当治疗的机会减少。原住民居民比例较高的地区显示出超出一般社会经济劣势影响的风险,而大城市社区居民对近期干预措施的利用率有所增加。

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