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澳大利亚的急性冠状动脉综合征:我们现在的状况以及未来的走向?

Acute coronary syndrome in Australia: Where are we now and where are we going?

作者信息

Nadel James, Hewitt Timothy, Horton Damien

机构信息

University of Notre Dame Australia, Sydney.

出版信息

Australas Med J. 2014 Mar 31;7(3):149-56. doi: 10.4066/AMJ.2014.1921. eCollection 2014.

Abstract

BACKGROUND

Acute coronary syndrome (ACS) is a significant contributor to both morbidity and mortality in Australia. Generally speaking, sufferers of ACS who live in rural areas and are treated at rural hospitals have poorer outcomes than those living in metropolitan areas.

AIMS

To characterise the differences in the management and outcomes of rural and metropolitan populations in the context of ACS, as well as identify factors responsible for these differences and suggest how they may be addressed.

METHOD

A review of the current literature surrounding ACS in Australia was undertaken. Through the MEDLINE/PubMed database a thorough search using the terms "acute coronary syndrome" and "Australia" identified 460 papers for review, excluding abstracts and adding "rural", "metropolitan", "reperfusion", and "outcomes" to this search narrowed the results to 149 papers for review. Data was also extracted from the Australian Institute of Health and Welfare and other Australian government publications. The review draws on insights from both local and international resources and seeks to provide an understanding of the contemporary landscape of ACS in both rural and metropolitan Australia. The review is broken down into three key sections: An outline of the 2011 National Heart Foundation of Australia/Cardiac Society of Australia and New Zealand (NHF/CSANZ) guidelines and adjuvant tools used in the assessment and treatment of ACS, and to what extent these guidelines have been implemented clinically.An exploration of the current landscape of ACS in Australia and identification of the disparities facing rural populations compared to those in metropolitan areas.Discussion of the factors that are resulting in poorer outcomes for ACS sufferers and suggestions of novel approaches towards addressing these factors.

CONCLUSION

Disparities exist between the management and outcomes of rural and metropolitan populations experiencing ACS. While the causes of these discrepancies are multifactorial; the onus is on the healthcare system to effectively reduce associated morbidity and mortality. Improvements in the management of ACS may be achieved through a continued reduction in call-to-needles time via the use of remote and mobile thrombolysis services as well as improvements in in-hospital risk assessment in order to flag and investigate those at risk of ACS.

摘要

背景

急性冠状动脉综合征(ACS)是澳大利亚发病和死亡的重要原因。一般来说,居住在农村地区并在农村医院接受治疗的ACS患者,其治疗结果比居住在大城市地区的患者更差。

目的

描述急性冠状动脉综合征背景下农村和大城市人群在治疗管理及结果方面的差异,确定造成这些差异的因素,并提出解决这些差异的建议。

方法

对澳大利亚目前有关急性冠状动脉综合征的文献进行综述。通过MEDLINE/PubMed数据库,使用“急性冠状动脉综合征”和“澳大利亚”等关键词进行全面检索,共识别出460篇可供综述的论文,排除摘要后,再添加“农村”“大城市”“再灌注”和“结果”等关键词进行检索,结果缩小至149篇可供综述的论文。数据还从澳大利亚卫生与福利研究所及其他澳大利亚政府出版物中提取。该综述借鉴了本地和国际资源的见解,旨在让人们了解澳大利亚农村和大城市地区急性冠状动脉综合征的当代情况。该综述分为三个关键部分:2011年澳大利亚国家心脏基金会/澳大利亚和新西兰心脏学会(NHF/CSANZ)指南概述以及用于急性冠状动脉综合征评估和治疗的辅助工具,以及这些指南在临床中的实施程度。探讨澳大利亚急性冠状动脉综合征的现状,以及确定农村人口与大城市人口相比所面临的差异。讨论导致急性冠状动脉综合征患者治疗结果较差的因素,并提出解决这些因素的新方法建议。

结论

急性冠状动脉综合征患者在农村和大城市地区的治疗管理及结果存在差异。虽然这些差异的原因是多方面的,但医疗系统有责任有效降低相关的发病率和死亡率。通过使用远程和移动溶栓服务持续缩短呼叫到穿刺时间,以及改善医院内风险评估以识别和调查有急性冠状动脉综合征风险的患者,可能会改善急性冠状动脉综合征的治疗管理。

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