Lakhani Aly, Maas Luis
Department of Internal Medicine, Gastroenterology division, William Beaumont Hospital, Royal Oak, MI 48067, USA.
South Med J. 2008 May;101(5):554-5. doi: 10.1097/SMJ.0b013e31816bf5eb.
Pancreatic panniculitis (PP) is a rare cutaneous eruption that is associated with severe pancreatic disease. A patient presented with a fever, joint pains, and an erythematous rash with draining pustules that had spread from his legs to his arms over 4 months. Thorough investigation revealed stage IV acinar cell carcinoma of the pancreas. The rash was a result of necrotizing PP. The variable cutaneous manifestations of internal malignancies may challenge primary care physicians and dermatologists when patients present without findings associated with malignancy. Panniculitis should be kept in mind in the differential diagnosis of inflamed appearing nodules and pustules with an erythematous base, particularly when they are progressive and unrelenting.
胰腺性脂膜炎（PP）是一种罕见的皮肤疹，与严重的胰腺疾病相关。一名患者出现发热、关节疼痛以及伴有引流脓疱的红斑疹，该皮疹在4个月内从腿部蔓延至手臂。全面检查发现为胰腺IV期腺泡细胞癌。皮疹是坏死性PP的结果。当患者没有出现与恶性肿瘤相关的体征时，内部恶性肿瘤的各种皮肤表现可能会给初级保健医生和皮肤科医生带来挑战。在鉴别诊断伴有红斑基底的炎性结节和脓疱时，应考虑脂膜炎，尤其是当它们呈进行性且持续不缓解时。
