Toffol Laura De, Pavoni Chiara, Baccetti Tiziano, Franchi Lorenzo, Cozza Paola
Department of Orthodontics, University of Rome Tor Vergata, Italy.
Angle Orthod. 2008 May;78(3):561-73. doi: 10.2319/030207-108.1.
To assess the scientific evidence on the effectiveness of early orthopedic treatment in Class III subjects.
A literature survey was performed by applying the Medline database (Entrez PubMed). The survey covered the period from January 1966 to December 2005 and used the Medical Subject Headings (MeSH). The following study types that reported data on the effects of Class III treatment with orthopedic appliances (facial mask, chincup, FR-3) on intermaxillary sagittal and vertical relationships were included: randomized clinical trials (RCTs), and prospective and retrospective longitudinal controlled clinical trials (CCTs) with untreated Class III controls.
The search strategy resulted in 536 articles. After selection according to criteria for inclusion and exclusion, 19 articles qualified for the final review analysis. One RCT and 18 CCTs were retrieved.
The quality standard of the retrieved investigations ranged from low (four studies) to medium/high (five studies). Data derived from medium/high quality research described over 75% of success of orthopedic treatment of Class III malocclusion (RME and facial mask therapy) at a follow-up observation 5 years after the end of orthopedic treatment.
评估早期正畸治疗对III类错颌患者有效性的科学证据。
通过应用Medline数据库（Entrez PubMed）进行文献检索。检索涵盖1966年1月至2005年12月期间，并使用医学主题词（MeSH）。纳入以下报告了使用正畸矫治器（面罩、颏兜、FR - 3）治疗III类错颌对颌间矢状向和垂直向关系影响数据的研究类型：随机临床试验（RCT），以及以未经治疗的III类错颌患者为对照的前瞻性和回顾性纵向对照临床试验（CCT）。
检索策略共得到536篇文章。根据纳入和排除标准进行筛选后，有19篇文章符合最终综述分析的要求。检索到1项RCT和18项CCT。
检索到的研究质量标准从低（4项研究）到中/高（5项研究）不等。来自中/高质量研究的数据表明，在正畸治疗结束5年后的随访观察中，III类错颌畸形（扩弓矫治和面罩治疗）正畸治疗的成功率超过75%。
