Green Robin, Davis Gloria, Price David
Department of Paediatrics and Child Health, University of Pretoria, South Africa.
Prim Care Respir J. 2008 Dec;17(4):212-6. doi: 10.3132/pcrj.2008.00027.
A number of studies from around the world have indicated that asthma morbidity is still unacceptably high. In the AIRE study over one-third of children and half of the adults reported daytime symptoms at least once a week. This study was conducted to understand the impact (including the impact on health-related quality of life) of asthma on South African asthmatics.
General Practitioners (GPs) and pharmacists in South Africa were randomly identified from the Medical Association database. These individuals were approached and asked to recruit asthmatic patients to complete a questionnaire. The questionnaire inquired about symptoms, quality of life, complications, trigger factors, associated allergic conditions, medication used, medication preference, medication adherence and concerns about the condition.
3347 respondents returned their demographic data but only 710 met the criteria for analysis, ie. had asthma and were presently on controller medication. Symptom analysis revealed that 21.4% of respondents were coughing on most days, 25.6% were wheezing on most days, and 22.8% were experiencing night-time symptoms on most days. Symptoms were exacerbated by exercise in 56.9%, while nocturnal wakening due to asthma occurred in 36.9% more than four times per week. Only 35.1% of respondents had not missed school or work in the preceding year. 45.4% of individuals worry about side effects of asthma therapy.
This study indicates that there is under-treatment, inappropriate treatment and/or lack of patient education for asthma patients in South Africa. The data support the notion that poor therapy and/or poor patient adherence has an enormous impact on the health-related quality of life of South Africa's asthmatics.
来自世界各地的多项研究表明,哮喘发病率仍然高得令人无法接受。在AIRE研究中,超过三分之一的儿童和一半的成年人报告每周至少出现一次日间症状。本研究旨在了解哮喘对南非哮喘患者的影响(包括对健康相关生活质量的影响)。
从医学协会数据库中随机挑选南非的全科医生(GP)和药剂师。与这些人联系并要求他们招募哮喘患者来完成一份问卷。问卷询问了症状、生活质量、并发症、触发因素、相关过敏状况、使用的药物、药物偏好、药物依从性以及对病情的担忧。
3347名受访者返回了他们的人口统计学数据,但只有710人符合分析标准,即患有哮喘且目前正在使用控制药物。症状分析显示,21.4%的受访者大多数日子都在咳嗽,25.6%的受访者大多数日子都在喘息,22.8%的受访者大多数日子都有夜间症状。56.9%的受访者运动时症状会加重,36.9%的受访者每周因哮喘夜间醒来超过四次。在前一年,只有35.1%的受访者没有缺课或旷工。45.4%的人担心哮喘治疗的副作用。
本研究表明,南非哮喘患者存在治疗不足、治疗不当和/或缺乏患者教育的情况。数据支持这样一种观点,即治疗不佳和/或患者依从性差对南非哮喘患者的健康相关生活质量有巨大影响。