Lanier Bobby Quentin, Nayak Anjuli
Pediatrics/Immunology, University of North Texas Health Science Center, Fort Worth, TX 76132, USA.
Postgrad Med. 2008 Nov;120(4):58-66. doi: 10.3810/pgm.2008.11.1939.
The frequency of nighttime asthma symptoms is an important measure of asthma severity. This study was designed to determine the prevalence of daytime and nighttime symptoms in adults and children with asthma and to evaluate the impact of nighttime symptoms on sleep and daytime activities.
An online survey was conducted among adults (> 18 years) and mothers of children aged 2 to 17 years with asthma. The survey included questions on daytime and nighttime asthma symptoms and asthma controller medication. Invitations to complete the survey were sent to 6349 members of a global opinion panel who were identified as having asthma. Data collection was from April to May 2005.
A total of 1600 invited panelists responded to the survey. Overall, 61% of participants reported nighttime asthma symptoms and 74% reported daytime asthma symptoms. Asthma-related sleep difficulties occurred approximately 4 times per week in adults and approximately 3 times per week in children. A significantly greater proportion of adults than children reported bothersome symptoms in the morning on awakening. Wheezing and difficulty breathing were reported in a greater proportion of adults, whereas coughing was reported in a greater proportion of children. A greater proportion of adults than children reported feelings of tiredness and impaired activity on days after experiencing nighttime symptoms. Absenteeism and lateness were more commonly reported by mothers of children with asthma than by other adults.
The prevalence of reported asthma symptoms, particularly nighttime symptoms, and the effects of nighttime symptoms on sleep and daytime activities indicates that survey participants had poorly controlled asthma.
夜间哮喘症状的发生频率是衡量哮喘严重程度的一项重要指标。本研究旨在确定成人和儿童哮喘患者白天和夜间症状的患病率，并评估夜间症状对睡眠和白天活动的影响。
对年龄大于18岁的成人以及2至17岁哮喘儿童的母亲进行了一项在线调查。该调查包括有关白天和夜间哮喘症状以及哮喘控制药物的问题。向全球意见小组中被确定患有哮喘的6349名成员发送了完成调查的邀请。数据收集时间为2005年4月至5月。
共有1600名受邀小组成员回复了调查。总体而言，61%的参与者报告有夜间哮喘症状，74%报告有白天哮喘症状。与哮喘相关的睡眠困难在成人中约每周发生4次，在儿童中约每周发生3次。报告早晨醒来时有令人烦恼症状的成人比例显著高于儿童。报告喘息和呼吸困难的成人比例更高，而报告咳嗽的儿童比例更高。报告在经历夜间症状后的次日感到疲倦和活动受影响的成人比例高于儿童。哮喘儿童的母亲比其他成人更常报告孩子旷课和迟到的情况。
所报告的哮喘症状的患病率，尤其是夜间症状，以及夜间症状对睡眠和白天活动的影响表明，调查参与者的哮喘控制不佳。
