Korsakov I N, Voskanian S E, Korot'ko G F
Eksp Klin Gastroenterol. 2007(6):84-7, 131.
Dynamics of cholecystokinin-like, secretin and somatostatin immunoreactivity of blood plasma and extracts of duodenal mucosa, frequency of acute pancreatitis (AP) after the resection of the duodenum was studied on not purebred dogs. Rising of a secretin concentration in blood plasma after the clinoid resection of the duodenum, accompanied by decreasing of its concentration in duodenal mucosa, was revealed. Decreasing of cholecystokinin concentration in a neutral extract was revealed. In 24 hours alter resection of the duodenum AP was observed in 38% of cases, infusion of the lorglumide was reduced the frequency of this complication up to 6.2% (p<0.05).
在非纯种犬身上研究了血浆和十二指肠黏膜提取物中胆囊收缩素样、促胰液素和生长抑素免疫反应性的动态变化，以及十二指肠切除术后急性胰腺炎（AP）的发生率。发现十二指肠岩斜区切除术后血浆中促胰液素浓度升高，同时十二指肠黏膜中促胰液素浓度降低。中性提取物中胆囊收缩素浓度降低。十二指肠切除术后24小时，38%的病例出现AP，输注洛谷酰胺可将该并发症的发生率降至6.2%（p<0.05）。
