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小儿腹膜透析复杂先天性心脏病术后长枝木霉纵隔炎和腹膜炎致死

Fatal post-operative Trichoderma longibrachiatum mediastinitis and peritonitis in a paediatric patient with complex congenital cardiac disease on peritoneal dialysis.

机构信息

Department of Pediatric and Adolescent Medicine, Division of Pediatric Infectious Diseases, Mayo Clinic College of Medicine and Mayo Eugenio Litta Children's Hospital, 200 First Street SW, Rochester, MN 55905, USA.

Department of Pediatric and Adult Allergy/Immunology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

出版信息

J Med Microbiol. 2011 Dec;60(Pt 12):1869-1871. doi: 10.1099/jmm.0.030718-0. Epub 2011 Jul 28.

DOI:10.1099/jmm.0.030718-0
PMID:21799200
Abstract

Trichoderma longibrachiatum is an emerging pathogen in immunocompromised patients. We report a case of Trichoderma post-operative mediastinitis and peritonitis in a child with complex congenital cardiac disease and functional asplenia. The patient was treated unsuccessfully, initially with caspofungin alone followed by a combination of voriconazole (systemic and topical), caspofungin and intraperitoneal amphotericin B.

摘要

长枝木霉是免疫功能低下患者的一种新兴病原体。我们报告了一例复杂先天性心脏病和功能性无脾儿童术后纵隔炎和腹膜炎合并长枝木霉感染的病例。该患者最初单独使用卡泊芬净治疗无效，随后联合使用伏立康唑（全身和局部）、卡泊芬净和腹腔内两性霉素 B 治疗。

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