Menter Alan, Gottlieb Alice, Feldman Steven R, Van Voorhees Abby S, Leonardi Craig L, Gordon Kenneth B, Lebwohl Mark, Koo John Y M, Elmets Craig A, Korman Neil J, Beutner Karl R, Bhushan Reva
Baylor University Medical Center, Dallas, Texas, USA.
J Am Acad Dermatol. 2008 May;58(5):826-50. doi: 10.1016/j.jaad.2008.02.039.
Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population. In this first of 5 sections of the guidelines of care for psoriasis, we discuss the classification of psoriasis; associated comorbidities including autoimmune diseases, cardiovascular risk, psychiatric/psychologic issues, and cancer risk; along with assessment tools for skin disease and quality-of-life issues. Finally, we will discuss the safety and efficacy of the biologic treatments used to treat patients with psoriasis.
银屑病是一种常见的慢性炎症性多系统疾病,主要表现为皮肤和关节症状,影响约2%的人口。在本银屑病护理指南五部分中的第一部分,我们将讨论银屑病的分类;相关的合并症,包括自身免疫性疾病、心血管风险、精神/心理问题和癌症风险;以及皮肤病和生活质量问题的评估工具。最后,我们将讨论用于治疗银屑病患者的生物治疗的安全性和有效性。