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水疱性口炎病毒糖蛋白的糖基化位点

Glycosylation sites of vesicular stomatitis virus glycoprotein.

作者信息

Robertson J S, Etchison J R, Summers D F

出版信息

J Virol. 1976 Sep;19(3):871-8. doi: 10.1128/JVI.19.3.871-878.1976.

Abstract

Detailed analysis on DEAE-Sephadex of the tryptic digestion products of the glycoprotein from vesicular stomatitis virus grown in HeLa suspension cultures revealed the presence of two major and several minor sugar-labeled species. The minor tryptic glycopeptides were converted to one of the two major glycopeptide species by treatment with neuraminidase. Thus, vesicular stomatitis virus glycoprotein contains only two oligosaccharide side chains that are heterogeneous in their sialic acid content.

摘要

对在HeLa悬浮培养物中生长的水泡性口炎病毒糖蛋白的胰蛋白酶消化产物进行的DEAE - 葡聚糖详细分析表明,存在两种主要的和几种次要的糖标记物种。通过用神经氨酸酶处理,次要的胰蛋白酶糖肽被转化为两种主要糖肽物种之一。因此,水泡性口炎病毒糖蛋白仅含有两个在唾液酸含量上异质的寡糖侧链。

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本文引用的文献

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