Chekalina S I, Medvedev V N, Firsova P P
Vopr Onkol. 1991;37(6):723-7.
Parameters of functional status of the hemostatic system were studied in 76 breast and lung cancer patients in the course of radiotherapy using TTC-10 hypoxic gas mixture (oxygen--10% and nitrogen--90%) as radioprotector. The thrombophilic status of the blood in breast and lung cancer patients established prior to treatment was accounted for by increased functional activity of platelets, increased capillary blood coagulability, formation of dense clot and inhibition of fibrinolysis. In the course of hypoxyradiotherapy, blood thrombogeneity becomes lower due to a decrease in platelet adhesion.
在76例乳腺癌和肺癌患者接受放疗期间,使用TTC - 10低氧气体混合物(氧气10%和氮气90%)作为辐射防护剂,研究了止血系统功能状态参数。治疗前确定的乳腺癌和肺癌患者血液的血栓形成倾向表现为血小板功能活性增加、毛细血管血液凝固性增加、致密凝块形成以及纤维蛋白溶解受抑制。在低氧放疗过程中,由于血小板黏附性降低,血液的血栓形成性降低。