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一种通过术前强化伽马远距离治疗和腔内热疗联合治疗食管癌和贲门癌的方法

[A method for the combined treatment of cancer of the esophagus and cardia by using intensive preoperative gamma teletherapy and intracavity hyperthermia].

作者信息

Ganul V L, Okulov L V, Nochka V I, Galakhin K A, Troitskaia I N

出版信息

Vopr Onkol. 1991;37(6):728-30.

PMID:1843153
Abstract

Local intracavitary hyperthermia and simultaneous intensive-concentrated irradiation were used in 23 patients with esophageal cancer and 64 cases of cardioesophageal malignancy prior to surgery. The procedure for thermometry is described. Hyperthermia was carried out after the second and fifth (out of six) radiation fractions, thermotolerability being taken into account. Complete and partial response rate was 72.7% in the study group compared to 56.5% in controls. The volume fraction of viable parenchyma dropped to 2.1 +/- 0.2% (16.6 +/- 1.5% in controls) whereas the injury index according to Lavnikova rose to 95.0% (58.7% in controls).

摘要

对23例食管癌患者和64例食管贲门恶性肿瘤患者在手术前采用局部腔内热疗并同时进行强化集中照射。描述了测温程序。热疗在第二次和第五次(共六次)放疗后进行,同时考虑了热耐受性。研究组的完全缓解率和部分缓解率为72.7%,而对照组为56.5%。存活实质组织的体积分数降至2.1±0.2%(对照组为16.6±1.5%),而根据拉夫尼科娃法计算的损伤指数升至95.0%(对照组为58.7%)。

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