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[营养对成年慢性腹泻患者治疗及康复的影响]

[Nutritional implications on treatment and recovery of adult patients with chronic diarrhea].

作者信息

Dichi I, Papini-Berto S J, Dichi J B, Di Lello A, Victória C R, Burini R C

机构信息

Laboratório de Bioquímica Nutricional e Metabólica, Hospital das Clínicas da Faculdade de Medicina de Botucatu-UNESP.

出版信息

Arq Gastroenterol. 1991 Jul-Sep;28(3):86-92.

PMID:1843243
Abstract

The nutritional assessment by 24 hour-dietary recall, anthropometry and blood-components measurements was undertaken in 23 adult patients, 17 males and 6 females suffering of chronic diarrhea from pancreatitis (30%), inflammatory bowel disease (22%), short intestine syndrome (9%) and unknown diarrhea (35%). The nutritional assessment was done at the entry and repeated at the discharge of the hospitalization that averaged 35 days, during which the patients received specific medical treatment along with obstipating diets. The hospitalization resulted in overall improvement of the patients either clinically by reducing their defecation rate or nutritionally by increasing their protein-energy intake and the values of anthropometry and blood components (albumin, free-tryptophan and lymphocytes). When the patients where divided into two groups based on their fecal-fat output one could note the better nutritional response of the group showing steatorrhea than the non-steatorrhea group, with the serum albumin and the arm-muscle circumference being discriminatory between groups. However even in the better recovered patients the indicative values of a satisfactory nutritional status were not accomplished. Thus, these data suggest that besides the overall nutritional improvement seen in the studied chronic diarrhea patients the full-nutrition recovering would demand either or both a longer hospitalization and/or an early-aggressive nutritional support.

摘要

对23例成年患者进行了24小时饮食回顾、人体测量和血液成分测量的营养评估,其中17例男性和6例女性患有慢性腹泻,病因包括胰腺炎(30%)、炎症性肠病(22%)、短肠综合征(9%)和不明原因腹泻(35%)。营养评估在入院时进行,并在平均住院35天出院时重复进行,在此期间患者接受了特定的药物治疗以及便秘饮食。住院治疗使患者在临床上通过降低排便率得到整体改善,或在营养上通过增加蛋白质能量摄入以及人体测量和血液成分(白蛋白、游离色氨酸和淋巴细胞)的值得到改善。当根据粪便脂肪排出量将患者分为两组时,可以注意到出现脂肪泻的组比无脂肪泻组的营养反应更好,血清白蛋白和上臂肌肉周长在两组之间具有区分性。然而,即使在恢复较好的患者中,也未达到令人满意的营养状况的指示值。因此,这些数据表明,除了在所研究的慢性腹泻患者中看到的整体营养改善外,完全恢复营养可能需要更长时间的住院治疗和/或早期积极的营养支持。

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