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[痤疮是由“错误”菌株的痤疮丙酸杆菌定植引起的吗?痤疮丙酸杆菌在痤疮中作用的综述]

[Is acne caused by colonization with the "wrong" strain of Propionibacterium acnes? A review of the role of Propionibacterium acnes in acne].

作者信息

Lomholt Hans Bredsted, Kilian Mogens

机构信息

Aarhus Universitet, Institut for Medicinsk Mikrobiologi og Immunologi.

出版信息

Ugeskr Laeger. 2008 Apr 7;170(15):1234-7.

Abstract

Acne is still a major problem, and treatment options are far from ideal. A number of studies suggest that the species Propionibacterium acnes plays an important role in the pathogenesis, and new data point towards molecular mechanisms by which the organism is able to trigger the host inflammatory response. The current knowledge on P. acnes in relation to acne is reviewed.

摘要

痤疮仍然是一个主要问题,而且治疗方案远非理想。多项研究表明,痤疮丙酸杆菌在发病机制中起着重要作用,新数据指向该生物体能够触发宿主炎症反应的分子机制。本文综述了目前关于痤疮丙酸杆菌与痤疮相关的知识。

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