Walker J L, Smith G H, Gaston M S, Robinson C M
Department of Orthopaedics, Edinburgh Royal Infirmary, Little France, Dalkeith Road, Edinburgh EH16 4SU, UK.
Emerg Med J. 2008 May;25(5):305-6. doi: 10.1136/emj.2007.055848.
Compartment syndrome as a result of simvastatin-induced myositis is extremely rare. This case discusses a patient with spontaneous onset compartment syndrome that necessitated four-compartment fasciotomy. A thorough investigation into its cause highlighted statin-induced myositis as the most likely aetiological agent. When investigating a patient with unexplained spontaneous compartment syndrome it is important to consider drug-induced myositis. This case reinforces the difficulty faced in diagnosing spontaneous compartment syndrome.
辛伐他汀诱发的肌炎导致的骨筋膜室综合征极为罕见。本病例讨论了一名患有自发性骨筋膜室综合征的患者,该患者需要进行四室筋膜切开术。对其病因的深入调查突出了他汀类药物诱发的肌炎是最可能的病因。在调查患有不明原因自发性骨筋膜室综合征的患者时,考虑药物诱发的肌炎很重要。本病例强化了诊断自发性骨筋膜室综合征所面临的困难。