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经食管多普勒超声心动图成像及血流测量用于诊断左冠状动脉狭窄

[Transesophageal Doppler echocardiographic imaging and blood flow measurements for the diagnosis of stenotic left coronary arteries].

作者信息

Yamada S, Morita H, Mizushige K, Hirabayashi K, Tanimoto T, Matsuo H

机构信息

Second Department of Internal Medicine, Kagawa Medical School.

出版信息

J Cardiol. 1991;21(3):539-49.

PMID:1843504
Abstract

To evaluate the usefulness of transesophageal Doppler echocardiography (TEE) in diagnosing left coronary artery (LCA) stenosis, we studied 26 patients with 33 proximal LCA lesions, including 5 with lesions of the left main trunk (LMT), 21 proximal anterior descending arteries (LAD), 7 proximal circumflex arteries (LCx), and 20 with normal coronary arteries. We measured blood flow velocity along the LCA using the pulsed Doppler mode (PD) and obtained velocities at multiple neighboring sites in 13 normal coronary arteries and in 12 of 26 LMTs or LADs with lesions. In all 13 normals, peak velocity tended to decline towards the periphery. By contrast, in one LMT and 10 LADs with lesions, marked increase in peak velocity (1.7 to 3.9 times) was observed at the sites diagnosed as stenotic lesions by coronary angiography. Using two-dimensional echocardiography (2DE), 24 LMTs including 3 with lesions, 4 LADs including 3 with lesions and 13 LCxs including 4 with lesions were imaged. Among them, 3 LMT, one LAD and 2 LCx lesions were correctly diagnosed. The diagnostic ratio by both PD and 2DE was 60% for LMT (PD: 20%, 2DE: 60%), 48% for LAD (PD: 48%, 2DE: 5%) and 29% for LCx (PD: 0%, 2DE: 29%) lesions. In conclusion, TEE proved to be useful in diagnosing proximal LCA stenosis. The coronary flow measurement by PD especially has the potentiality for the diagnosis of proximal LAD stenosis.

摘要

为评估经食管多普勒超声心动图(TEE)在诊断左冠状动脉(LCA)狭窄中的作用,我们研究了26例患者的33处LCA近端病变,其中包括5例左主干(LMT)病变、21例近端前降支动脉(LAD)病变、7例近端回旋支动脉(LCx)病变以及20例冠状动脉正常者。我们使用脉冲多普勒模式(PD)测量沿LCA的血流速度,并在13例正常冠状动脉以及26例LMT或LAD病变患者中的12例病变处的多个相邻部位获取速度。在所有13例正常者中,峰值速度倾向于向周边下降。相比之下,在1例LMT和10例LAD病变患者中,在冠状动脉造影诊断为狭窄病变的部位观察到峰值速度显著增加(1.7至3.9倍)。使用二维超声心动图(2DE)对24例LMT(包括3例病变)、4例LAD(包括3例病变)和13例LCx(包括4例病变)进行成像。其中,3例LMT病变、1例LAD病变和2例LCx病变被正确诊断。LMT病变的PD和2DE联合诊断率为60%(PD:20%,2DE:60%),LAD病变为48%(PD:48%,2DE:5%),LCx病变为29%(PD:0%,2DE:29%)。总之,TEE被证明在诊断LCA近端狭窄中是有用的。通过PD测量冠状动脉血流尤其具有诊断LAD近端狭窄的潜力。

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