Ravipati Nagesh B, McLemore Elisabeth C, Schlinkert Richard T, Argueta Rodolfo
Division of General Surgery, Mayo Clinic Arizona, Scottsdale, AZ, USA.
Am J Surg. 2008 Jun;195(6):799-802. doi: 10.1016/j.amjsurg.2007.09.036. Epub 2008 Apr 24.
Approximately 2% of ectopic parathyroid glands reside within the mediastinum in a location that requires a thoracic approach.
All patients with mediastinal parathyroid tumors who underwent anterior mediastinotomy were included in this review.
Over the course of 16 years, 10 patients with primary hyperparathyroidism underwent anterior mediastinotomy. There were 6 men and 4 women with a median age of 65. Seven patients had undergone at least one previous cervical exploration. Preoperative calcium levels were 11.3 +/- .8 mg/dL. Nine patients had preoperative localization with radionuclide scans and 9 patients also had preoperative computerized tomography or magnetic resonance imaging scans. An abnormal gland was removed in all cases. Nine of 10 patients had normalization of their calcium levels.
Anterior mediastinotomy after preoperative imaging has proven to be a technically feasible, safe, and effective method for the surgical management of patients with sporadic primary hyperparathyroidism and mediastinal parathyroid tumors.
约2%的异位甲状旁腺位于纵隔内,其位置需要采用开胸手术入路。
本综述纳入了所有接受前纵隔切开术的纵隔甲状旁腺肿瘤患者。
在16年期间,10例原发性甲状旁腺功能亢进患者接受了前纵隔切开术。其中男性6例,女性4例,中位年龄为65岁。7例患者此前至少接受过一次颈部探查。术前血钙水平为11.3±0.8mg/dL。9例患者术前行放射性核素扫描定位,9例患者还术前行计算机断层扫描或磁共振成像扫描。所有病例均切除了异常腺体。10例患者中有9例血钙水平恢复正常。
术前影像学检查后行前纵隔切开术已被证明是治疗散发性原发性甲状旁腺功能亢进和纵隔甲状旁腺肿瘤患者的一种技术可行、安全有效的手术方法。