Arrich Jasmin, Müllner Marcus, Lalouschek Wolfgang, Greisenegger Stefan, Crevenna Richard, Herkner Harald
Department of Emergency Medicine, Medical University Vienna, Vienna General Hospital, Währinger Gürtel 18-20/6D, Austria.
Stroke. 2008 Jul;39(7):2066-72. doi: 10.1161/STROKEAHA.107.506147. Epub 2008 Apr 24.
Female patients and patients with a lower level socioeconomic status (SES) often experience less favorable health outcomes. We aimed to investigate whether gender and socioeconomic status of patients with acute ischemic stroke or transient ischemic attack are associated with different diagnostic and treatment strategies.
The risk factors of interest were gender and SES. We predefined our diagnostic and treatment end points according to current stroke guidelines and used multivariate models to adjust for age, stroke severity, and comorbidities.
A total of 2606 patients were included in the analysis. Women were less likely to receive antiplatelet agents within the first 48 hours after admission (OR: 0.59, 95% CI: 0.53 to 0.89) and more likely to have their blood glucose measured on admission than men (OR: 1.52, 95% CI: 1.1 to 2.1). With higher SES patients were more likely to receive a TTE or TTE during hospital stay. Women were almost twice as likely to receive a prescription for antidepressants at discharge OR of 1.96 (95% CI: 1.48 to 2.59).
Socioeconomic status and gender are associated with some diagnostic and treatment differences of acute ischemic stroke. Most pronounced were a reduced chance for women to receive antiplatelet therapy on admission and a reduced chance for a TTE and TEE with a lower level of SES, whereas the rate of thrombolysis was unbiased by gender and SES.
女性患者以及社会经济地位(SES)较低的患者往往健康结局较差。我们旨在调查急性缺血性卒中或短暂性脑缺血发作患者的性别和社会经济地位是否与不同的诊断和治疗策略相关。
感兴趣的风险因素为性别和SES。我们根据当前的卒中指南预先设定诊断和治疗终点,并使用多变量模型对年龄、卒中严重程度和合并症进行校正。
共有2606例患者纳入分析。女性在入院后48小时内接受抗血小板药物治疗的可能性较小(比值比:0.59,95%置信区间:0.53至0.89),且入院时测量血糖的可能性高于男性(比值比:1.52,95%置信区间:1.1至2.1)。SES较高的患者在住院期间更有可能接受经胸超声心动图(TTE)或经食管超声心动图(TEE)检查。女性出院时接受抗抑郁药处方的可能性几乎是男性的两倍,比值比为1.96(95%置信区间:1.48至2.59)。
社会经济地位和性别与急性缺血性卒中的一些诊断和治疗差异相关。最明显的是,女性入院时接受抗血小板治疗的机会减少,SES较低的患者接受TTE和TEE检查的机会减少,而溶栓率不受性别和SES的影响。