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神经囊尾蚴病所致脑积水继发帕金森综合征

Parkinsonism Secondary to Hydrocephalus Caused by Neurocysticercosis.

作者信息

Oliveira Sebastião Carlos de Sousa, Monteiro Dina Andressa Martins, Silva Giselle Furtado, Santos Lucas Tadeu Rocha, Ribeiro Espártaco Moraes Lima

机构信息

Neurological Surgery, Federal University of Ceara, Sobral, BRA.

Neurology, Federal University of Ceara, Sobral, BRA.

出版信息

Cureus. 2020 Apr 29;12(4):e7887. doi: 10.7759/cureus.7887.

DOI:10.7759/cureus.7887
PMID:32489741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7255557/
Abstract

The diagnosis of parkinsonism is established by the presence of tremor, stiffness and bradykinesia alongside with neurological examination, requiring the exclusion of secondary causes such as stroke, hydrocephalus and infectious diseases. Included in this last category, neurocysticercosis is a disease caused by Taenia solium, with a variable clinical presentation that can include epileptic seizures, hydrocephalus and rarely parkinsonism. In the reported case, the syndrome is a consequence of lesions in the nigrostriatal dopaminergic pathway caused by the implant and mass effect of the cysticercus. The authors report a case of parkinsonism in a 59-year-old woman with a previous history of neurocysticercosis who presented with hydrocephalus on magnetic resonance imaging exam. The patient was treated with pharmacological therapy and ventriculoperitoneal shunt, progressing with amelioration of the symptoms presented.

摘要

帕金森综合征的诊断是通过震颤、僵硬和运动迟缓的症状以及神经学检查来确定的,这需要排除中风、脑积水和传染病等继发性病因。在最后这一类病因中,神经囊尾蚴病是由猪带绦虫引起的一种疾病,其临床表现多样,可包括癫痫发作、脑积水,很少出现帕金森综合征。在本报告的病例中,该综合征是由囊尾蚴的植入和占位效应导致黑质纹状体多巴胺能通路受损所致。作者报告了一例59岁女性帕金森综合征病例,该患者既往有神经囊尾蚴病史,磁共振成像检查显示有脑积水。患者接受了药物治疗和脑室腹腔分流术,症状有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a44/7255557/c22d595f486d/cureus-0012-00000007887-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a44/7255557/05bf928fcf07/cureus-0012-00000007887-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a44/7255557/0ac75fa26057/cureus-0012-00000007887-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a44/7255557/ecb4d6d7724f/cureus-0012-00000007887-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a44/7255557/84e48b753cfb/cureus-0012-00000007887-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a44/7255557/c22d595f486d/cureus-0012-00000007887-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a44/7255557/05bf928fcf07/cureus-0012-00000007887-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a44/7255557/0ac75fa26057/cureus-0012-00000007887-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a44/7255557/ecb4d6d7724f/cureus-0012-00000007887-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a44/7255557/84e48b753cfb/cureus-0012-00000007887-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a44/7255557/c22d595f486d/cureus-0012-00000007887-i05.jpg

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Neurocysticercosis and movement disorders: A literature review.

本文引用的文献

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Cysticercosis and taeniasis cases diagnosed at two referral medical institutions, Belgium, 1990 to 2015.1990 年至 2015 年在比利时两家转诊医疗机构诊断的囊尾蚴病和带绦虫病病例。
Euro Surveill. 2019 Aug;24(35). doi: 10.2807/1560-7917.ES.2019.24.35.1800589.
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Diagnosis and Treatment of Neurocysticercosis: 2017 Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH).神经囊尾蚴病的诊断与治疗:美国感染病学会(IDSA)和美国热带医学与卫生学会(ASTMH)2017年临床实践指南。
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神经囊尾蚴病与运动障碍:文献综述
Brain Circ. 2020 Dec 29;6(4):225-241. doi: 10.4103/bc.bc_48_20. eCollection 2020 Oct-Dec.
Parkinsonism and other movement disorders in 23 cases of neurocysticercosis.
神经囊虫病 23 例中的帕金森病和其他运动障碍。
Parkinsonism Relat Disord. 2017 Sep;42:47-53. doi: 10.1016/j.parkreldis.2017.06.009. Epub 2017 Jun 20.
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Neurocysticercosis: Diagnostic problems & current therapeutic strategies.神经囊尾蚴病:诊断问题与当前治疗策略
Indian J Med Res. 2016 Sep;144(3):319-326. doi: 10.4103/0971-5916.198686.
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Revised diagnostic criteria for neurocysticercosis.神经囊尾蚴病的修订诊断标准。
J Neurol Sci. 2017 Jan 15;372:202-210. doi: 10.1016/j.jns.2016.11.045. Epub 2016 Nov 21.
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MDS clinical diagnostic criteria for Parkinson's disease.帕金森病的MDS临床诊断标准。
Mov Disord. 2015 Oct;30(12):1591-601. doi: 10.1002/mds.26424.
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Medicine (Baltimore). 2011 Jan;90(1):81-86. doi: 10.1097/MD.0b013e318206d13e.
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Clin Neurol Neurosurg. 2008 Jul;110(7):718-21. doi: 10.1016/j.clineuro.2008.03.008. Epub 2008 Apr 25.