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[神经囊尾蚴病中的左旋多巴敏感性帕金森症]

[L-dopa sensitive Parkinsonism in neurocysticercosis].

作者信息

López I Cabo, Bermejo P García, Espiga P J García Ruiz, Tapia D Quiñones

机构信息

Servicio de Neurología, Fundación Jiménez Díaz, Madrid.

出版信息

Neurologia. 2008 Mar;23(2):119-21.

PMID:18322832
Abstract

INTRODUCTION

Neurocysticercosis (NC) is a chronic parasitary disease that may have different neurological manifestations, such as seizures, dementia or obstructive hydrocephalus. On rare occasions, pictures secondary to hydrocephalia may occur with Parkinsonian syndrome.

CASE REPORT

We present the case of a 29-year old woman with serologically confirmed NC and obstructive hydrocephalia secondary to a cyst in the IV ventricle. The patient required repeated ventricle-peritoneal shunt replacement because of valvular malfunction and obstructive hydrocephalia. She developed Parkinsonian's syndrome, which subsided after combined treatment with cysticidal drugs and L-dopa.

DISCUSSION

Parkinsonian syndrome is an atypical presentation in NC. In this case, the above-mentioned profile is found within the context of multiple valvular malfunctions who nature is reversible after appropriate treatment. It seems to be related with increases in intraventricular cerebrospinal fluid pressure. We can conclude that Parkinsonian syndromes may be one more expression of NC. This acquires greater importance according to its context, in addition to the limited presence of similar cases in our environment in the literature.

摘要

引言

神经囊尾蚴病(NC)是一种慢性寄生虫病,可能有不同的神经表现,如癫痫发作、痴呆或梗阻性脑积水。极少数情况下,脑积水继发的症状可能伴有帕金森综合征。

病例报告

我们报告一例29岁女性患者,血清学确诊为NC,因第四脑室囊肿继发梗阻性脑积水。由于瓣膜功能障碍和梗阻性脑积水,患者需要反复更换脑室-腹腔分流管。她出现了帕金森综合征,在使用杀囊药物和左旋多巴联合治疗后症状缓解。

讨论

帕金森综合征在NC中是一种非典型表现。在本病例中,上述情况出现在多次瓣膜功能障碍的背景下,经过适当治疗后其性质是可逆的。它似乎与脑室内脑脊液压力升高有关。我们可以得出结论,帕金森综合征可能是NC的另一种表现形式。鉴于其背景情况,以及文献中我们所处环境中类似病例的有限存在,这一点变得更加重要。

相似文献

1
[L-dopa sensitive Parkinsonism in neurocysticercosis].[神经囊尾蚴病中的左旋多巴敏感性帕金森症]
Neurologia. 2008 Mar;23(2):119-21.
2
Reversible parkinsonism following ventriculoperitoneal shunt in a patient with obstructive hydrocephalus secondary to intraventricular neurocysticercosis.一例因脑室内神经囊尾蚴病继发梗阻性脑积水而行脑室腹腔分流术后出现可逆性帕金森综合征的患者
Clin Neurol Neurosurg. 2008 Jul;110(7):718-21. doi: 10.1016/j.clineuro.2008.03.008. Epub 2008 Apr 25.
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Fourth ventricular neurocystercercosis presenting with acute hydrocephalus.第四脑室神经囊尾蚴病伴发急性脑积水。
J Clin Neurosci. 2011 Jun;18(6):867-9. doi: 10.1016/j.jocn.2010.12.002. Epub 2011 Apr 19.
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[L-dopa effective parkinsonism appeared after shunt revision of the aqueductal stenosis: report of two cases].[导水管狭窄分流术修正术后出现左旋多巴有效的帕金森症:两例报告]
No To Shinkei. 2000 May;52(5):425-9.
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[Rapidly progressive parkinsonism that developed one year after ventriculoperitoneal shunting for idiopathic aqueductal stenosis: a case report].[特发性导水管狭窄脑室腹腔分流术后一年出现的快速进展性帕金森病:一例报告]
Brain Nerve. 2010 May;62(5):527-31.
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[A case of severe parkinsonism induced by failure of ventriculo-peritoneal shunt for aqueductal stenosis].[一例因导水管狭窄脑室腹腔分流失败导致的严重帕金森综合征病例]
Rinsho Shinkeigaku. 2003 Jul;43(7):427-30.
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Parkinsonism associated with neurocysticercosis.与神经囊尾蚴病相关的帕金森综合征
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[Bruns' syndrome: description of a case of neurocysticercosis with pathological study].
Neurologia. 2005 Mar;20(2):86-9.
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[A case of neurocysticercosis with multiple intraparenchymal and intraventricular cysts].[一例伴有多发脑实质内和脑室内囊肿的神经囊尾蚴病]
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[Ventricular haemorrhage in preterm neonates and posthemorrhagic hydrocephalus. Proposal of a management protocol based on early ventriculo-peritoneal shunt].[早产儿脑室内出血及出血后脑积水。基于早期脑室-腹腔分流术的治疗方案建议]
Neurocirugia (Astur). 2009 Feb;20(1):15-24.

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