López I Cabo, Bermejo P García, Espiga P J García Ruiz, Tapia D Quiñones
Servicio de Neurología, Fundación Jiménez Díaz, Madrid.
Neurologia. 2008 Mar;23(2):119-21.
Neurocysticercosis (NC) is a chronic parasitary disease that may have different neurological manifestations, such as seizures, dementia or obstructive hydrocephalus. On rare occasions, pictures secondary to hydrocephalia may occur with Parkinsonian syndrome.
We present the case of a 29-year old woman with serologically confirmed NC and obstructive hydrocephalia secondary to a cyst in the IV ventricle. The patient required repeated ventricle-peritoneal shunt replacement because of valvular malfunction and obstructive hydrocephalia. She developed Parkinsonian's syndrome, which subsided after combined treatment with cysticidal drugs and L-dopa.
Parkinsonian syndrome is an atypical presentation in NC. In this case, the above-mentioned profile is found within the context of multiple valvular malfunctions who nature is reversible after appropriate treatment. It seems to be related with increases in intraventricular cerebrospinal fluid pressure. We can conclude that Parkinsonian syndromes may be one more expression of NC. This acquires greater importance according to its context, in addition to the limited presence of similar cases in our environment in the literature.
神经囊尾蚴病(NC)是一种慢性寄生虫病,可能有不同的神经表现,如癫痫发作、痴呆或梗阻性脑积水。极少数情况下,脑积水继发的症状可能伴有帕金森综合征。
我们报告一例29岁女性患者,血清学确诊为NC,因第四脑室囊肿继发梗阻性脑积水。由于瓣膜功能障碍和梗阻性脑积水,患者需要反复更换脑室-腹腔分流管。她出现了帕金森综合征,在使用杀囊药物和左旋多巴联合治疗后症状缓解。
帕金森综合征在NC中是一种非典型表现。在本病例中,上述情况出现在多次瓣膜功能障碍的背景下,经过适当治疗后其性质是可逆的。它似乎与脑室内脑脊液压力升高有关。我们可以得出结论,帕金森综合征可能是NC的另一种表现形式。鉴于其背景情况,以及文献中我们所处环境中类似病例的有限存在,这一点变得更加重要。