血管内技术、医院手术量与腹主动脉瘤手术死亡率
Endovascular technology, hospital volume, and mortality with abdominal aortic aneurysm surgery.
作者信息
Dimick Justin B, Upchurch Gilbert R
机构信息
Michigan Surgical Collaborative for Outcomes Research and Evaluation, Ann Arbor, MI 48104, USA.
出版信息
J Vasc Surg. 2008 Jun;47(6):1150-4. doi: 10.1016/j.jvs.2008.01.054. Epub 2008 Apr 28.
OBJECTIVE
To determine whether the introduction of endovascular technology changed the relationship of hospital volume to mortality with abdominal aortic aneurysm repair.
METHODS
Data from all hospitals in the United States that performed abdominal aortic aneurysm surgery on Medicare patients from 2001 to 2003 were obtained from the national Medicare database. The primary outcome variable was death <or=30 days of operation or before hospital discharge. We determined the effect of total hospital volume on operative mortality for all types of repair and for endovascular and open repair separately. All analyses were adjusted for patient risk using logistic regression.
RESULTS
The proportion of abdominal aortic aneurysms repaired with an endovascular approach increased from 27% to 39% during the 3-year study period. Hospital volume was significantly related to operative mortality in all comparisons. Mortality rates were 80% higher at hospitals in the lowest vs the highest quartile of total volume (odds ratio [OR], 1.81; 95% confidence interval [CI], 1.62-2.04) when considering all types of repair together. A similar relationship between total hospital volume and mortality was found when separately examining open repair (OR, 1.52; 95% CI, 1.33-1.73) and endovascular repair (OR, 1.68; 95% CI, 1.32-2.22). Higher-volume hospitals were more likely to use the endovascular approach. The highest-volume hospitals used the endovascular approach 44% of the time compared with only 18% at the lowest-volume hospitals. This greater use of the endovascular procedure at high-volume hospitals accounted for 37% of the difference in mortality between high- and low-volume hospitals.
CONCLUSION
As the endovascular repair becomes more widespread, the relationship between hospital volume and operative mortality still remains. High-volume hospitals are more likely to use the endovascular approach, and this explains a significant portion of the observed impact of hospital volume on mortality.
目的
确定血管内技术的引入是否改变了腹主动脉瘤修复手术中医院手术量与死亡率之间的关系。
方法
从国家医疗保险数据库中获取2001年至2003年期间为医疗保险患者进行腹主动脉瘤手术的美国所有医院的数据。主要结局变量是术后≤30天或出院前死亡。我们分别确定了医院总手术量对所有类型修复手术、血管内修复手术和开放修复手术的手术死亡率的影响。所有分析均使用逻辑回归对患者风险进行了校正。
结果
在3年的研究期间,采用血管内修复方法的腹主动脉瘤比例从27%增加到了39%。在所有比较中,医院手术量与手术死亡率均显著相关。综合考虑所有类型的修复手术时,手术量处于最低四分位数的医院与最高四分位数的医院相比,死亡率高出80%(比值比[OR],1.81;95%置信区间[CI],1.62 - 2.04)。分别检查开放修复手术(OR,1.52;95%CI,1.33 - 1.73)和血管内修复手术(OR,1.68;95%CI,1.32 - 2.22)时,也发现医院总手术量与死亡率之间存在类似关系。手术量较高的医院更有可能采用血管内修复方法。手术量最高的医院44%的时间采用血管内修复方法,而手术量最低的医院仅为18%。高手术量医院更多地使用血管内修复方法,这占高手术量医院与低手术量医院死亡率差异的37%。
结论
随着血管内修复手术的日益普及,医院手术量与手术死亡率之间的关系仍然存在。高手术量医院更有可能采用血管内修复方法,这解释了观察到的医院手术量对死亡率影响的很大一部分。