狒狒体内天然牙形态生物玻璃的植入：初步报告。

The implantation of natural tooth form bioglasses in baboons. A preliminary report.

作者信息

Stanley H R, Hench L, Going R, Bennett C, Chellemi S J, King C, Ingersoll N, Ethridge E, Kreutziger K

出版信息

Oral Surg Oral Med Oral Pathol. 1976 Sep;42(3):339-56. doi: 10.1016/0030-4220(76)90168-7.

Abstract

This report describes a 6-month screening study comparing the tissue responses of several bioglass natural tooth implants in adult female baboons. The dental implants were designed to elicit osteogenesis at the interface of the implant and the oral tissues. This is in contrast to those types of implant materials that are merely biologically acceptable. Incisor teeth were extracted, dupplicated in bioglass, returned to the natural sockets, and splinted to the adjacent natural tooth, where they remained splinted for 3 months and then free standing for an additional 3 months. Microscopic evaluation revealed distinct histopathologic characteristics with certain bioglass formulas, such as ankylosis, a pseudofibrous capsule with fibers running parallel to the root surface, or an apparently true periodontal membrane with properly oriented Sharpey's fibers. True cementogenesis was not found.

摘要

本报告描述了一项为期6个月的筛查研究，该研究比较了几种生物玻璃天然牙植入物在成年雌性狒狒体内的组织反应。这些牙植入物旨在在植入物与口腔组织的界面处引发骨生成。这与那些仅仅是生物可接受的植入材料类型形成对比。拔除切牙，用生物玻璃复制，放回天然牙槽窝，并与相邻的天然牙固定在一起，在此固定3个月，然后再独立放置3个月。显微镜评估显示，某些生物玻璃配方具有明显的组织病理学特征，如骨粘连、纤维与牙根表面平行排列的假纤维囊，或具有排列正确的沙比纤维的明显真正的牙周膜。未发现真正的牙骨质生成。