Hsu Shu-Hui, Roberson Peter L, Chen Yu, Marsh Robin B, Pierce Lori J, Moran Jean M
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA.
Phys Med Biol. 2008 May 21;53(10):2593-606. doi: 10.1088/0031-9155/53/10/010. Epub 2008 Apr 25.
Skin dose assessment for chest wall radiotherapy is important to ensure sufficient dose to the surface target volume without excessive skin reaction. This study quantified changes to the surface doses as a function of bolus material for conventional and intensity modulated radiation therapy (IMRT) tangential fields. Three types of bolus materials (2 mm solid, 2 mm fine mesh and 3.2 mm large mesh Aquaplast) were compared with Superflab. Surface dose measurements were performed using an Attix parallel plate chamber in a flat solid water phantom at 0 degrees , 45 degrees and 70 degrees incident angles. Over-response correction factors were applied to the Attix chamber results for different incident angles. Surface dose measurements on an anthropomorphic phantom were done using a thermoluminescent dosimeter extrapolation method. Dose characteristics of Superflab and solid Aquaplast were within 2% of solid water material. No significant differences (within 3%) in the surface dose were found between conventional and IMRT tangential techniques. The bolus effect was large for chest wall tangential radiotherapy, with up to an 82% increase using 2 mm fine mesh Aquaplast. The dosimetric effect of different Aquaplast materials has been quantified in this work. These materials can be used to create a custom bolus with potentially better reproducibility of placement.
胸壁放射治疗的皮肤剂量评估对于确保在不过度产生皮肤反应的情况下给予表面靶区足够剂量至关重要。本研究量化了常规和调强放射治疗(IMRT)切线野中作为填充物材料函数的表面剂量变化。将三种类型的填充物材料(2毫米实心、2毫米细网和3.2毫米大网Aquaplast)与Superflab进行了比较。使用Attix平行板电离室在扁平固体水模体中于0度、45度和70度入射角进行表面剂量测量。针对不同入射角对Attix电离室结果应用了超响应校正因子。使用热释光剂量计外推法在人体模体上进行表面剂量测量。Superflab和实心Aquaplast的剂量特性在固体水材料的2%以内。在常规和IMRT切线技术之间未发现表面剂量有显著差异(在3%以内)。对于胸壁切线放射治疗,填充物效应很大,使用2毫米细网Aquaplast时表面剂量增加高达82%。在本研究中已对不同Aquaplast材料的剂量学效应进行了量化。这些材料可用于制作定制填充物,其放置的可重复性可能更好。