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临床6兆伏光子束剂量测定中,丸剂下空气间隙的影响。

Influence of Air Gap under Bolus in the Dosimetry of a Clinical 6 MV Photon Beam.

作者信息

Lobo Dilson, Banerjee Sourjya, Srinivas Challapalli, Ravichandran Ramamoorthy, Putha Suman Kumar, Prakash Saxena P U, Reddy Shreyas, Sunny Johan

机构信息

Department of Radiation Oncology, Kasturba Medical College (A Constituent Institution of Manipal Academy of Higher Education), Mangalore, Karnataka, India.

出版信息

J Med Phys. 2020 Jul-Sep;45(3):175-181. doi: 10.4103/jmp.JMP_53_20. Epub 2020 Oct 13.

Abstract

AIM

In some situations of radiotherapy treatments requiring application of tissue-equivalent bolus material (e.g., gel bolus), due to material's rigid/semi-rigid nature, undesirable air gaps may occur beneath it because of irregularity of body surface. The purpose of this study was to evaluate the dosimetric parameters such as surface dose (D), depth of dose maximum (d), and depth dose along central axis derived from the percentage depth dose (PDD) curve of a 6 MV clinical photon beam in the presence of air gaps between the gel bolus and the treatment surface.

MATERIALS AND METHODS

A bolus holder was designed to hold the gel bolus sheet to create an air gap between the bolus and the radiation field analyzer's (RFA-300) water surface. PDD curves were taken for field sizes of 5 cm × 5 cm, 10 cm × 10 cm, 15 cm × 15 cm, 20 cm × 20 cm, and 25 cm × 25 cm, with different thicknesses of gel bolus (0.5, 1.0, and 1.5 cm) and air gap (from 0.0 to 3.0 cm), using a compact ionization chamber (CC13) with RFA-300 keeping 100 cm source-to-surface (water) distance. The dosimetric parameters, for example, "D," "d" and difference of PDD (maximum air gap vs. nil air gap), were analyzed from the obtained PDD curves.

RESULTS

Compared to ideal conditions of full contact of bolus with water surface, it has been found that there is a reduction in "D" ranging from 14.8% to 3.2%, 14.9% to 1.1%, and 12.6% to 0.7% with the increase of field size for 0.5, 1.0, and 1.5 cm thickness of gel boluses, respectively, for maximum air gap. The "d" shows a trend of moving away from the treatment surface, and the maximum shift was observed for smaller field size with thicker bolus and greater air gap. The effect of air gap on PDD is minimal (≤1%) beyond 0.4 cm depth for all bolus thicknesses and field sizes except for 5 cm × 5 cm with 1.5 cm bolus thickness.

CONCLUSIONS

The measured data can be used to predict the probable effect on therapeutic outcome due to the presence of inevitable air gaps between the bolus and the treatment surface.

摘要

目的

在一些需要使用组织等效填充材料(如凝胶填充剂)的放射治疗情况下,由于材料的刚性/半刚性性质,由于体表不规则,其下方可能会出现不理想的气隙。本研究的目的是评估在凝胶填充剂与治疗表面之间存在气隙的情况下,从6 MV临床光子束的百分深度剂量(PDD)曲线得出的表面剂量(D)、剂量最大值深度(d)和中心轴深度剂量等剂量学参数。

材料与方法

设计了一个填充剂固定器来固定凝胶填充剂片,以在填充剂与辐射场分析仪(RFA - 300)的水面之间形成气隙。使用紧凑型电离室(CC13)与RFA - 300,在源到表面(水)距离为100 cm的情况下,针对5 cm×5 cm、10 cm×10 cm、15 cm×15 cm、20 cm×20 cm和25 cm×25 cm的射野尺寸,以及不同厚度(0.5、1.0和1.5 cm)的凝胶填充剂和气隙(从0.0到3.0 cm)获取PDD曲线。从获得的PDD曲线中分析剂量学参数,例如“D”、“d”以及PDD的差值(最大气隙与无气隙情况相比)。

结果

与填充剂与水面完全接触的理想条件相比,已发现对于0.5、1.0和1.5 cm厚度的凝胶填充剂,随着射野尺寸增加,最大气隙时“D”的降低幅度分别为14.8%至3.2%、14.9%至1.1%和12.6%至0.7%。“d”显示出远离治疗表面的趋势,对于较小射野尺寸、较厚填充剂和较大气隙,观察到最大偏移。除了1.5 cm填充剂厚度的5 cm×5 cm射野尺寸外,对于所有填充剂厚度和射野尺寸,在深度超过0.4 cm时,气隙对PDD的影响最小(≤1%)。

结论

所测量的数据可用于预测由于填充剂与治疗表面之间不可避免地存在气隙而可能对治疗结果产生的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72b1/7810143/a541773db419/JMP-45-175-g001.jpg

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