半圆柱状射束挡块在 6MV 光子束治疗早期声门型喉癌中的应用价值
Usefulness of Semi-cylindrical Beam Spoiler in Treatment of Early Glottic Cancer Using 6 MV Photon Beam.
机构信息
Department of Radiation Oncology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Republic of Korea.
Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Republic of Korea.
出版信息
In Vivo. 2022 Jan-Feb;36(1):465-472. doi: 10.21873/invivo.12726.
BACKGROUND/AIM: To assess the dosimetric influence of a semi-cylindrical beam spoiler (sCBS) for the treatment of early glottic cancer using a 6 MV photon beam.
PATIENTS AND METHODS
The 2D dose distributions were also calculated and measured with and without the sCBS and with a 0.5 cm thick bolus. A retrospective study of 8 patients treated between 2012 and 2018 was performed.
RESULTS
The 2D dose distributions obtained from the treatment planning system (TPS) and film measurements were in good agreement. In the planning study, the V, V, conformal index (CI), and homogeneity index (HI) of all pPTVs for the sCBS plans were better than those for the open field plans (p<0.01). Especially, sCBS plans had better skin sparing effect than bolus plans (p<0.05).
CONCLUSION
The sCBS of the 6 MV photon beam could be a useful tool for the treatment of early glottic cancers.
背景/目的：评估使用 6MV 光子束治疗早期声门癌时半圆柱型射野挡块（sCBS）的剂量学影响。
患者和方法
还计算并测量了有和没有 sCBS 以及 0.5cm 厚的填充物的二维剂量分布。对 2012 年至 2018 年间治疗的 8 例患者进行了回顾性研究。
结果
治疗计划系统（TPS）和胶片测量得到的二维剂量分布吻合较好。在计划研究中，sCBS 计划的所有 pPTV 的 V、V、适形指数（CI）和均匀性指数（HI）均优于开放野计划（p<0.01）。特别是，sCBS 计划具有比填充物计划更好的皮肤保护效果（p<0.05）。
结论
6MV 光子束的 sCBS 可能是治疗早期声门癌的有用工具。
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