多核苷酸的构象分析。I. 具有高反式构象的聚（8,2'-S-环腺苷酸）的有利左手螺旋模型。
Conformational analysis of polynucleotides. I. The favorable left-handed helical model for the poly(8,2'-S-cycloadenylic acid) with high anti conformation.
作者信息
Fujii S, Tomita K
出版信息
Nucleic Acids Res. 1976 Aug;3(8):1973-84. doi: 10.1093/nar/3.8.1973.
Abstract
- Energy calculations have shown that poly (8,2'-S-cycloadenylic aicd) can form left-handed helices owing to the high anti conformation. 2) Two favorable left-handed helices are characterized by axial translation per residue (Z=4.3 and 3.6A) and by rotations per residue (theta= 40 degrees and -25 degrees). 3) The proposed helical models might be stable in aqueous solution and is well explicable of the optical property of this compound.
摘要
- 能量计算表明，聚（8,2'-S-环腺苷酸）由于高反式构象可形成左手螺旋。2) 两种有利的左手螺旋的特征在于每个残基的轴向平移（Z = 4.3和3.6埃）以及每个残基的旋转（θ = 40度和 -25度）。3) 所提出的螺旋模型在水溶液中可能是稳定的，并且很好地解释了该化合物的光学性质。
相似文献
1
Conformational analysis of polynucleotides. I. The favorable left-handed helical model for the poly(8,2'-S-cycloadenylic acid) with high anti conformation.多核苷酸的构象分析。I. 具有高反式构象的聚（8,2'-S-环腺苷酸）的有利左手螺旋模型。
Nucleic Acids Res. 1976 Aug;3(8):1973-84. doi: 10.1093/nar/3.8.1973.
2
Analysis of the possible helical structures of nucleic acids and polynucleotides. Application of (n-h) plots.核酸和多核苷酸可能的螺旋结构分析。（n-h）图的应用。
Nucleic Acids Res. 1976 Mar;3(3):729-47. doi: 10.1093/nar/3.3.729.
3
Salt-induced Z-A-Z transition sequence in the mixed ribo-deoxyribo copolymer poly(rG-dC) X poly(rG-dC).盐诱导的混合核糖 - 脱氧核糖共聚物聚（rG-dC）×聚（rG-dC）中的Z-A-Z转变序列。
Proc Natl Acad Sci U S A. 1984 Dec;81(23):7284-7. doi: 10.1073/pnas.81.23.7284.
4
Structure of poly 8-bromoadenylic acid; conformational studies by CPF energy calculations.聚8-溴腺苷酸的结构；通过CPF能量计算进行的构象研究
Nucleic Acids Res. 1977 Aug;4(8):2573-92. doi: 10.1093/nar/4.8.2573.
5
Effect of terminal achiral and chiral residues on the conformational behaviour of poly Δ(z)Phe and analysis of various interactions.末端非手性和手性残基对聚Δ(z)苯丙氨酸构象行为的影响及各种相互作用分析。
Indian J Biochem Biophys. 2003 Aug;40(4):265-73.
6
The influence of a chiral amino acid on the helical handedness of PNA in solution and in crystals.手性氨基酸对溶液和晶体中肽核酸螺旋手性的影响。
J Biomol Struct Dyn. 2004 Feb;21(4):495-502. doi: 10.1080/07391102.2004.10506943.
7
Molecular mechanics studies on poly(purine).poly(pyrimidine) sequences in DNA: polymorphism and local variability.DNA中聚嘌呤-聚嘧啶序列的分子力学研究：多态性与局部变异性
Biopolymers. 1989 Feb;28(2):531-48. doi: 10.1002/bip.360280202.
8
Interactions of anti-poly[d(G-br5C)] IgG with synthetic, viral and cellular Z DNAs.抗聚[d（G-br5C）]IgG与合成的、病毒的和细胞的Z-DNA的相互作用。
J Biomol Struct Dyn. 1984 Mar;1(5):1081-107. doi: 10.1080/07391102.1984.10507506.
9
Recognition of Z-RNA and Z-DNA determinants by polyamines in solution: experimental and theoretical studies.多胺在溶液中对Z-RNA和Z-DNA决定簇的识别：实验与理论研究
J Biomol Struct Dyn. 1988 Oct;6(2):299-309. doi: 10.1080/07391102.1988.10507714.
10
Left-handed helices for DNA: studies on poly[d(I-C)].DNA的左手螺旋：聚[d（I-C）]的研究
Proc Natl Acad Sci U S A. 1982 Oct;79(20):6109-13. doi: 10.1073/pnas.79.20.6109.
引用本文的文献
1
Conformational characteristics of the dimeric subunits of DNA from energy minimization studies. Mixed sugar-puckered dApdA, dApdT, dTpdA, and dTpdT.来自能量最小化研究的DNA二聚体亚基的构象特征。混合糖环构象的dApdA、dApdT、dTpdA和dTpdT。
Biophys J. 1981 Sep;35(3):731-52. doi: 10.1016/S0006-3495(81)84824-2.
2
Helix geometry of single stranded DNA 'A' and 'B' forms from minimum energy conformations of dimeric subunits.单链DNA“A”和“B”型的螺旋几何结构源自二聚体亚基的最低能量构象。
Nucleic Acids Res. 1978 Jan;5(1):127-37. doi: 10.1093/nar/5.1.127.
3
The influence of terminal 3', 5' phosphates on conformations of dApdA.3'、5' 末端磷酸对 dApdA 构象的影响。
Nucleic Acids Res. 1979;6(6):2165-78. doi: 10.1093/nar/6.6.2165.
4
Spatial configuration of ordered polynucleotide chains: a novel double helix.有序多核苷酸链的空间构型：一种新型双螺旋结构。
Proc Natl Acad Sci U S A. 1977 May;74(5):1775-9. doi: 10.1073/pnas.74.5.1775.
本文引用的文献
1
Polynucleotides. XXVI. Complex formation of polynucleotides derived from formycin and laurusin with cyclonucleoside oligonucleotides.多核苷酸。二十六。源自间型霉素和月桂霉素的多核苷酸与环核苷寡核苷酸的复合物形成
Nucleic Acids Res. 1974 Jul;1(7):907-17. doi: 10.1093/nar/1.7.907.
2
Stereochemistry of nucleic acids and their constituents. X. Solid-state base-stacking patterns in nucleic acid constituents and polynucleotides.核酸及其成分的立体化学。X.核酸成分和多核苷酸中的固态碱基堆积模式。
Biopolymers. 1971;10(1):175-219. doi: 10.1002/bip.360100113.
3
Stereochemistry of nucleic acids and polynucleotides. II. Allowed conformations of the monomer unit for different ribose puckerings.核酸与多核苷酸的立体化学。II. 不同核糖折叠形式下单体单元的允许构象。
Biochim Biophys Acta. 1970 Mar 19;204(1):49-59. doi: 10.1016/0005-2787(70)90489-2.
4
A highly stacked dinucleoside monophosphate derived from adenine 8-cyclonucleosides.一种源自腺嘌呤8-环核苷的高度堆积的二磷酸核苷单酯。
J Am Chem Soc. 1970 Jul 29;92(15):4735-6. doi: 10.1021/ja00718a046.
5
Stereochemistry of nucleic acids and polynucleotides. 3. Electronic charge distribution.核酸与多核苷酸的立体化学。3. 电子电荷分布。
Biopolymers. 1971;10(7):1159-67. doi: 10.1002/bip.360100707.
6
Optimised parameters for RNA double-helices.RNA双螺旋的优化参数。
Biochem Biophys Res Commun. 1972 Sep 26;48(6):1392-9. doi: 10.1016/0006-291x(72)90867-4.
7
Circular dichroism of polynucleotides: dimers as a function of conformation.多核苷酸的圆二色性：作为构象函数的二聚体
Biopolymers. 1972 Jan;11(1):225-34. doi: 10.1002/bip.1972.360110117.
8
Molecular structure of 2,2'-anhydro-1- -D-arabinofuranosyl cytosine hydrochloride (cyclo ara-C): a highly rigid nucleoside.
Biochem Biophys Res Commun. 1973 Jun 19;52(4):1348-53. doi: 10.1016/0006-291x(73)90649-9.
9
Backbone conformations in secondary and tertiary structural units of nucleic acids. Constraint in the phosphodiester conformation.核酸二级和三级结构单元中的主链构象。磷酸二酯构象的限制。
Proc Natl Acad Sci U S A. 1974 Sep;71(9):3325-8. doi: 10.1073/pnas.71.9.3325.
10
Left-handed helical polynucleotides with D-sugar phosphodiester backbones.
Nat New Biol. 1972 Nov 1;240(96):16-7. doi: 10.1038/newbio240016a0.
Zotero 插件