Eun Young Gyu, Kim Sung Wan, Kwon Kee Hwan, Byun Jae Yong, Lee Kun Hee
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Kyunghee University, #1 Hoegi-dong, Dongdaemun-gu, Seoul, 130-702, Korea.
Eur Arch Otorhinolaryngol. 2008 Dec;265(12):1495-500. doi: 10.1007/s00405-008-0688-7. Epub 2008 Apr 29.
This study aimed to evaluate the efficacy and safety of single-session radiofrequency tongue base reduction (RTBR) combined with uvulopalatopharyngoplasty (UPPP) for the treatment of obstructive sleep apnea syndrome (OSAS). Sixty-six patients with multilevel obstruction underwent single-session RTBR combined with UPPP. Snoring, Epworth sleepiness scale (ESS) and polysomnography were used to assess outcome before and 6 months after treatment. Sixty-six patients completed this study. Snoring level significantly decreased from 8.0 to 4.3. The mean ESS score significantly decreased from 11.4 to 7.5. The mean apnea-hypopnea index decreased significantly from 22.9 to 13.9. The overall success rate of the single-session RTBR combined with UPPP was 53.6%. Postoperative AHI in 50% of patients was normalized (AHI < 5). The success rates for patients with mild, moderate and severe OSAS were 62.5, 46.2 and 57.1%, respectively. There were two adverse effects, one ulceration of the tongue base and one transient taste change. Single-session RTBR combined with UPPP is an effective and safe treatment for OSAS patients with multilevel obstruction. It could be considered as first treatment for OSAS patients with multilevel obstruction, independent of the severity of OSAS.
本研究旨在评估单疗程射频舌根减容术(RTBR)联合悬雍垂腭咽成形术(UPPP)治疗阻塞性睡眠呼吸暂停综合征(OSAS)的疗效和安全性。66例存在多平面阻塞的患者接受了单疗程RTBR联合UPPP治疗。采用打鼾情况、爱泼沃斯嗜睡量表(ESS)和多导睡眠图评估治疗前及治疗后6个月的结果。66例患者完成了本研究。打鼾程度从8.0显著降至4.3。ESS平均评分从11.4显著降至7.5。平均呼吸暂停低通气指数从22.9显著降至13.9。单疗程RTBR联合UPPP的总体成功率为53.6%。50%患者术后的呼吸暂停低通气指数恢复正常(呼吸暂停低通气指数<5)。轻度、中度和重度OSAS患者的成功率分别为62.5%、46.2%和57.1%。出现了2例不良反应,1例舌根溃疡和1例短暂味觉改变。单疗程RTBR联合UPPP是治疗多平面阻塞OSAS患者的一种有效且安全的方法。对于多平面阻塞的OSAS患者,无论OSAS严重程度如何,均可将其视为首选治疗方法。