[毛细胞白血病的细胞学和免疫表型特征：6例报告]
[Cytology and immunophenotype features of hairy cell leukemia: 6 cases].
作者信息
Gouider Emna, Ben Salah Naouel, El Borgi Wijden, Hafsia Raouf
机构信息
Service d'Hématologie Biologique, Hôpital Aziza Othmana, Tunis, Tunisie.
出版信息
Tunis Med. 2008 Feb;86(2):118-21.
BACKGROUND
Hairy cell leukemia is a rare lymphoproliferative disorder.
AIM
with cytological and immunophenotypic features.
METHODS
We report 6 cases of hairy cell leukemia diagnosed in the Biological Department of Hematology at the Aziza Othmana Hospital of Tunis.
RESULTS
Hairy cells was observed in blood smears of 5 cases. Flow cytometry analysis shown monoclonal a monoclonal population B while gatinting on the expression of the CD19 and SSC signal. The positivity of the CD103 is noted in 5 cases and the CD11c signal is intense in all the cases.
CONCLUSION
Immunophenotype is of great interest in the diagnosis of hairy cell leukemia.
背景
毛细胞白血病是一种罕见的淋巴细胞增殖性疾病。
目的
具有细胞学和免疫表型特征。
方法
我们报告了在突尼斯阿齐扎·奥斯曼纳医院血液生物学部诊断的6例毛细胞白血病病例。
结果
5例患者的血涂片观察到毛细胞。流式细胞术分析显示在检测CD19和侧向散射光信号时出现单克隆B细胞群。5例患者CD103呈阳性，所有病例CD11c信号均强阳性。
结论
免疫表型对毛细胞白血病的诊断具有重要意义。
Zotero 插件