Ammari Lamia, Kilani Badreddine, Tiouiri Hanène, Kanoun Fakher, Goubontini Ahmed, Mnif Emna, Zouiten Fayçal, Chaker Emna, Ben Chaabane Taoufik
Department of Infectious Diseases, Rabta Hospital, Tunis, Tunisia.
Tunis Med. 2008 Feb;86(2):165-8.
Mucormycosis is a rare and invasive fungal infection, but frequently fatal when it occurs. It commonly affects patients with diabetes mellitus. The aim of this study is to assess the clinical presentation, radiological findings, management and prognosis of mucormycosis.
This retrospective study was conducted in the department of infectious diseases of Rabta hospital between January 1988 and December 2004 and included patients hospitalized for mucormycosis confirmed by mycological and/or histological findings.
the study is about four diabetic patients with mucormycosis (3 men and a woman). Three of them had diabetic ketoacidosis at the time of diagnosis. The infection was sinusal in 2 cases and rhinocerebral in the the other two cases. Treatment consisted in systemic amphotericin B combined with surgical debridement in 3 cases. A fatal outcome was noted in 2 cases.
Mucormycosis remains a severe infectious disease in diabetic patients. Early diagnosis and treatment is mandatory for a successful management of this infection.
毛霉病是一种罕见的侵袭性真菌感染，一旦发生往往致命。它通常影响糖尿病患者。本研究的目的是评估毛霉病的临床表现、影像学表现、治疗及预后。
本回顾性研究于1988年1月至2004年12月在拉卜塔医院传染病科进行，纳入因真菌学和/或组织学检查确诊为毛霉病而住院的患者。
该研究涉及4例毛霉病糖尿病患者（3男1女）。其中3例在诊断时患有糖尿病酮症酸中毒。2例感染为鼻窦型，另外2例为鼻脑型。3例患者的治疗包括全身使用两性霉素B联合手术清创。2例患者死亡。
毛霉病在糖尿病患者中仍然是一种严重的传染病。早期诊断和治疗对于成功控制这种感染至关重要。
