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糖尿病中的毛霉菌病

Mucormycosis in diabetes.

作者信息

Hopkins M A, Treloar D M

机构信息

College of Nursing, University of Florida, Gainesville, USA.

出版信息

Am J Crit Care. 1997 Sep;6(5):363-7.

PMID:9283673
Abstract

Mucormycosis is a rare opportunistic infection caused by ubiquitous fungi typically found in soil, spoiled foods, bread, and dust. The acute infection most commonly is rhinocerebral and is associated with metabolic acidosis. Mucormycosis spreads quickly and can progress from the paranasal area to the brain in a few days. In the case presented, a young diabetic woman had diabetic ketoacidosis and classic signs and symptoms of mucormycosis. Even after aggressive and appropriate treatment with surgical debridement and IV administration of amphotericin B, the fungus invaded the central nervous system. This article discusses current methods of treating mucormycosis and important critical care nursing considerations for patients who have the infection.

摘要

毛霉菌病是一种由普遍存在于土壤、变质食物、面包和灰尘中的真菌引起的罕见机会性感染。急性感染最常见于鼻脑部位,与代谢性酸中毒有关。毛霉菌病传播迅速,可在数天内从鼻旁区域蔓延至脑部。在本文所述病例中,一名年轻的糖尿病女性患有糖尿病酮症酸中毒及毛霉菌病的典型体征和症状。即便经过积极且恰当的手术清创及静脉注射两性霉素B治疗,真菌仍侵袭了中枢神经系统。本文讨论了毛霉菌病的当前治疗方法以及针对感染该疾病患者的重要重症护理注意事项。

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