Sadhu Samir Kumar, Khatun Amina, Ohtsuki Takashi, Ishibashi Masami
Graduate School of Pharmaceutical Sciences, Chiba University, Inage-ku, Chiba, Japan.
Planta Med. 2008 Jun;74(7):760-3. doi: 10.1055/s-2008-1074523. Epub 2008 Apr 29.
An androstanoid, hoyasterone (1), a sesquiterpene, 15-bulnesolic acid (2), and a phenolic compound, 1-(4-hydroxy-3-methoxyphenyl)-1-methoxypropan-2-ol (3), together with a known triterpene, dihydrocanaric acid, were isolated from Hoya parasitica. Structures were elucidated by 1 D and 2 D NMR and mass spectroscopic analysis. Among the isolated compounds, only dihydrocanaric acid exhibited growth inhibitory activity against both HeLa and SW480 cells.