Aponte José C, Estevez Yannick, Gilman Robert H, Lewis Walter H, Rojas Rosario, Sauvain Michel, Vaisberg Abraham J, Hammond Gerald B
Department of Chemistry, University of Louisville, Louisville, KY, U.S.A.
Planta Med. 2008 Mar;74(4):407-10. doi: 10.1055/s-2008-1034330.
A pharmacological screening of the ethanol extract and fractions of Blepharodon nitidum led to the isolation of fourteen compounds, two of which, 24-hydroperoxycycloart-25-en-3beta-ol and 25-hydroperoxycycloart-23-en-3beta-ol, exhibited in vitro anti- Mycobacterium tuberculosis and antileishmanial activities, as well as significant cytotoxic activity against a panel of human tumor cell lines.
对亮叶鳞始蕨乙醇提取物及其馏分进行的药理筛选，得到了14种化合物，其中两种，即24-氢过氧化环阿尔廷-25-烯-3β-醇和25-氢过氧化环阿尔廷-23-烯-3β-醇，表现出体外抗结核分枝杆菌和抗利什曼原虫活性，以及对一组人类肿瘤细胞系的显著细胞毒性活性。
