黑腹果蝇温度敏感型麻痹突变体的神经生理缺陷
Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster.
作者信息
Siddiqi O, Benzer S
出版信息
Proc Natl Acad Sci U S A. 1976 Sep;73(9):3253-7. doi: 10.1073/pnas.73.9.3253.
Abstract
A new temperature-sensitive paralytic mutant of Drosophila, comatose, is compared behaviorally and physiologically with the previously known types, para and shi. All three have different properties with respect to kinetics of paralysis at high temperature and recovery from paralysis; com is hypersensitive to paralysis by cooling. Neurophysiological experimeents indicate different mechanisms for paralysis in each of the mutants.
摘要
一种新的果蝇温度敏感型麻痹突变体——昏迷（comatose），在行为和生理方面与之前已知的类型——无钠（para）和颤抖（shi）进行了比较。在高温下麻痹的动力学以及从麻痹中恢复方面，这三种突变体都具有不同的特性；昏迷突变体对冷却引起的麻痹高度敏感。神经生理学实验表明，每种突变体的麻痹机制都不同。
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