Ikeda K, Kaplan W D
Proc Natl Acad Sci U S A. 1970 Jul;66(3):765-72. doi: 10.1073/pnas.66.3.765.
Hyperkinetic (1P), a behavioral mutant of Drosophila melanogaster, shows rhythmic leg-shaking action derived from mutation of a single, sex-linked gene. The neural mechanism governing this abnormal motor function consists of rhythmic bursts of activity produced by motor neurons located within the thoracic ganglion. The mechanism of the pattern formation was independent both of sensory information and higher centers in the central nervous system but endogenous within the ganglion. Two types of neurons which appear to be involved in the pattern formation were found within six limited regions.
运动亢进型(1P)是黑腹果蝇的一种行为突变体,表现出由单个性连锁基因突变引起的腿部节律性抖动行为。控制这种异常运动功能的神经机制由位于胸神经节内的运动神经元产生的节律性活动爆发组成。模式形成机制既不依赖于感觉信息,也不依赖于中枢神经系统中的高级中枢,而是神经节内源性的。在六个有限区域内发现了两种似乎参与模式形成的神经元。