Viral proteins interfering with antigen presentation target the major histocompatibility complex class I peptide-loading complex.
作者信息
Røder Gustav, Geironson Linda, Bressendorff Iain, Paulsson Kajsa
机构信息
Department of Experimental Immunology, Institute of International Health, Immunology and Microbiology, University of Copenhagen, Panum Institute, Copenhagen, Denmark.
出版信息
J Virol. 2008 Sep;82(17):8246-52. doi: 10.1128/JVI.00207-08. Epub 2008 Apr 30.
Abstract
摘要
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本文引用的文献
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Molecular architecture of the TAP-associated MHC class I peptide-loading complex.与抗原加工相关转运体（TAP）相关的MHC I类肽装载复合物的分子结构
J Immunol. 2007 Nov 1;179(9):5717-27. doi: 10.4049/jimmunol.179.9.5717.
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High-risk human papillomavirus E7 expression reduces cell-surface MHC class I molecules and increases susceptibility to natural killer cells.高危型人乳头瘤病毒E7表达降低细胞表面I类主要组织相容性复合体分子水平并增加对自然杀伤细胞的易感性。
Oncogene. 2008 Mar 13;27(12):1794-9. doi: 10.1038/sj.onc.1210798. Epub 2007 Sep 10.
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A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates.一种针对旧世界灵长类动物中爱泼斯坦-巴尔病毒及其近亲的CD8 + T细胞免疫逃逸蛋白。
J Exp Med. 2007 Aug 6;204(8):1863-73. doi: 10.1084/jem.20070256. Epub 2007 Jul 9.
4
Redox regulation of peptide receptivity of major histocompatibility complex class I molecules by ERp57 and tapasin.内质网蛋白57和塔帕辛对主要组织相容性复合体I类分子肽接受性的氧化还原调节
Nat Immunol. 2007 Aug;8(8):864-72. doi: 10.1038/ni1483. Epub 2007 Jul 1.
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Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer.通过塔帕辛-内质网蛋白57异二聚体将高亲和力肽选择性加载到主要组织相容性复合体I类分子上。
Nat Immunol. 2007 Aug;8(8):873-81. doi: 10.1038/ni1485. Epub 2007 Jul 1.
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Allele- and locus-specific recognition of class I MHC molecules by the immunomodulatory E3-19K protein from adenovirus.腺病毒免疫调节性E3-19K蛋白对I类主要组织相容性复合体分子的等位基因特异性和位点特异性识别。
J Immunol. 2007 Apr 1;178(7):4567-75. doi: 10.4049/jimmunol.178.7.4567.
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Multiple residues in the transmembrane helix and connecting peptide of mouse tapasin stabilize the transporter associated with the antigen-processing TAP2 subunit.小鼠塔帕辛跨膜螺旋和连接肽中的多个残基稳定了与抗原加工相关转运体的TAP2亚基。
J Biol Chem. 2007 Mar 30;282(13):9401-9410. doi: 10.1074/jbc.M610429200. Epub 2007 Jan 23.
8
Inhibition of heavy chain and beta2-microglobulin synthesis as a mechanism of major histocompatibility complex class I downregulation during Epstein-Barr virus replication.抑制重链和β2-微球蛋白合成作为爱泼斯坦-巴尔病毒复制过程中主要组织相容性复合体I类下调的一种机制。
J Virol. 2007 Feb;81(3):1390-400. doi: 10.1128/JVI.01999-06. Epub 2006 Nov 15.
9
Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing.氧化还原调节在抗原加工过程中促进MHC I类分子对最佳肽段的选择。
Cell. 2006 Oct 20;127(2):369-82. doi: 10.1016/j.cell.2006.08.041.
10
The first N-terminal transmembrane helix of each subunit of the antigenic peptide transporter TAP is essential for independent tapasin binding.抗原肽转运体TAP各亚基的首个N端跨膜螺旋对于独立结合TAP结合蛋白至关重要。
FEBS Lett. 2006 Jul 24;580(17):4091-6. doi: 10.1016/j.febslet.2006.06.053. Epub 2006 Jun 30.
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