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[伊夫雷亚 - 卡斯特拉蒙特医院43例急性阑尾炎和阑尾脓肿患者腹腔脓液的细菌学研究:需氧菌和厌氧菌的分离及药敏情况]

[Bacteriology of abdominal pus in 43 cases of acute appendicitis and appendiceal abscess at the Ivrea-Castellamonte Hospital, isolation of aerobic and anaerobic bacteria and drug sensitivity].

作者信息

Guasco C, Ronchetto F, Milani P, Stacchini E, Pistono P G

机构信息

Laboratorio Analisi Ospedale di Ivrea-Castellamonte.

出版信息

G Batteriol Virol Immunol. 1991 Jan-Dec;84(1-12):77-86.

PMID:1844922
Abstract

A retrospective study on the microbiology of abdominal pus from acute appendicitis or peritonitis was carried out by the authors. A total of 45 specimens were examined, 38 of them (84.4%) where found to be positive, of which 29 (76.3%) were polymicrobial and 9 (23.7%) were monomicrobial. The most represented species were Escherichia coli (28.4%), Bacteroides fragilis (7.8%), Streptococcus milleri (7.8%), Bacteroides oralis (3.9%) and Pseudomonas aeruginosa (3.9%). The polymicrobial associations more represented include Bacteroidaceae, Enterobacteriaceae and streptococcus genus. The most active drugs in vitro were found to be Piperacillin and Chloramphenicol, Cephalosporin (cefotaxime, ceftriaxone and cefoxitin) showed a good capability of being active against isolated microorganisms although they were less effective when used against anaerobic microorganisms then aerobic ones. On the contrary, Rifampicin, Metronidazole and Clindamycin were found to be quite effective against the anaerobes.

摘要

作者对急性阑尾炎或腹膜炎患者腹腔脓液进行了微生物学回顾性研究。共检查了45份标本,其中38份(84.4%)呈阳性,其中29份(76.3%)为多菌感染,9份(23.7%)为单菌感染。最常见的菌种为大肠埃希菌(28.4%)、脆弱拟杆菌(7.8%)、米勒链球菌(7.8%)、口腔拟杆菌(3.9%)和铜绿假单胞菌(3.9%)。最常见的多菌组合包括拟杆菌科、肠杆菌科和链球菌属。体外活性最强的药物为哌拉西林和氯霉素,头孢菌素(头孢噻肟、头孢曲松和头孢西丁)对分离出的微生物有良好的抗菌活性,尽管其对厌氧微生物的抗菌效果不如需氧微生物。相反,利福平、甲硝唑和克林霉素对厌氧菌相当有效。

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