Chapadeiro E, Florêncio R F, Afonso P C, Beraldo P S, de Jesus P C, Junqueira Júnior L F
Department of Clinical Medicine, Health Sciences School, University of Brasília, DF.
Rev Inst Med Trop Sao Paulo. 1991 Sep-Oct;33(5):337-41. doi: 10.1590/s0036-46651991000500001.
Ten male Wistar rats, chronically infected with Colombian, São Felipe (12SF) and Y strains of Trypanosoma cruzi and ten non-infected control animals were submitted to the bradycardia responsiveness test, an assessment of heart parasympathetic function, after phenylephrine injection. Six chagasic animals showed heart parasympathetic dysfunction characterized by reduction in the index of bradycardia baroreflex responsiveness, as compared with the control group. Microscopic examination of the atrial heart ganglia of chagasic rats showed ganglionitis, but no statistically significant reduction in the number of neurons.
十只慢性感染克氏锥虫哥伦比亚株、圣费利佩（12SF）株和Y株的雄性Wistar大鼠以及十只未感染的对照动物，在注射去氧肾上腺素后接受了心动过缓反应性测试，这是一种对心脏副交感神经功能的评估。与对照组相比，六只恰加斯病动物表现出心脏副交感神经功能障碍，其特征为心动过缓压力反射反应指数降低。对恰加斯病大鼠心房神经节的显微镜检查显示有神经节炎，但神经元数量没有统计学上的显著减少。
