Figuerêdo-Silva J, Coutinho-Netto J, Bestetti R B, Oliveira J S
Departamento de Patologia, Universidade Federal de Pernambuco, Recife, PE, Brasil.
Braz J Med Biol Res. 1989;22(6):737-40.
Isolated superfused rat atria release [3H]-acetylcholine when depolarized with 57 mM potassium. The depolarization-induced [3H]-acetylcholine overflow was significantly reduced in atria from chronically T. cruzi-infected rats with electrocardiographically characterized cardiopathy. This fact suggests the occurrence of functional alterations of cardiac parasympathetic control in these animals, probably related to cardiac ganglion cell destruction.
分离的灌注大鼠心房在用57 mM钾去极化时会释放[3H]-乙酰胆碱。在患有经心电图特征化的心肌病的慢性克氏锥虫感染大鼠的心房中，去极化诱导的[3H]-乙酰胆碱溢出显著减少。这一事实表明这些动物心脏副交感神经控制发生了功能改变，可能与心脏神经节细胞破坏有关。
