Lal Shantanu, Cheng Bin, Kaplan Selma, Softness Barney, Greenberg Ellen, Goland Robin S, Lalla Evanthia, Lamster Ira B
Division of Pediatric Dentistry, Columbia University College of Dental Medicine, P&S 3-454c, 630W 168th St, New York, NY 10032, USA.
Pediatrics. 2008 May;121(5):e1139-43. doi: 10.1542/peds.2007-1486.
The objective of this study was to evaluate tooth eruption in 6- to 14-year-old children with diabetes mellitus.
Tooth eruption status was assessed for 270 children with diabetes and 320 control children without diabetes. Data on important diabetes-related variables were collected. Analyses were performed using logistic regression models.
Children with diabetes exhibited accelerated tooth eruption in the late mixed dentition period (10-14 years of age) compared to healthy children. For both case patients and control subjects the odds of a tooth being in an advanced eruptive stage were significantly higher among girls than boys. There was also a trend associating gingival inflammation with expedited tooth eruption in both groups. No association was found between the odds of a tooth being in an advanced stage of eruption and hemoglobin A(1c) or duration of diabetes. Patients with higher body mass index percentile demonstrated statistically higher odds for accelerated tooth eruption, but the association was not clinically significant.
Children with diabetes exhibit accelerated tooth eruption. Future studies need to ascertain the role of such aberrations in dental development and complications such as malocclusion, impaired oral hygiene, and periodontal disease. The standards of care for children with diabetes should include screening and referral programs aimed at oral health promotion and disease prevention.
本研究的目的是评估6至14岁糖尿病患儿的牙齿萌出情况。
对270名糖尿病患儿和320名无糖尿病的对照儿童的牙齿萌出状况进行评估。收集重要的糖尿病相关变量的数据。使用逻辑回归模型进行分析。
与健康儿童相比,糖尿病患儿在混合牙列后期(10至14岁)牙齿萌出加速。对于病例患者和对照受试者,女孩牙齿处于萌出晚期的几率均显著高于男孩。两组中牙龈炎症与牙齿萌出加快之间也存在一种趋势。未发现牙齿处于萌出晚期的几率与糖化血红蛋白A1c或糖尿病病程之间存在关联。较高体重指数百分位数的患者牙齿萌出加速的几率在统计学上更高,但这种关联在临床上并不显著。
糖尿病患儿牙齿萌出加速。未来的研究需要确定这种异常在牙齿发育以及诸如错牙合、口腔卫生受损和牙周疾病等并发症中的作用。糖尿病患儿的护理标准应包括旨在促进口腔健康和预防疾病的筛查及转诊计划。