Alves Cresio, Menezes Rafaela, Brandão Marcia
Pediatric Endocrinology Service, Hospital Universitário Professor Edgard Santos, Faculty of Medicine, Federal University of Bahia, Bahia, Brazil.
Indian J Dent Res. 2012 Nov-Dec;23(6):758-62. doi: 10.4103/0970-9290.111254.
Although type 1 diabetes mellitus (T1DM) has a significant impact on oral health, its association with dental caries is yet not clear.
The aim of this study was to evaluate the salivary flow rate and caries in Brazilian youth with type 1 diabetes mellitus.
A Cross-sectional study was performed in a tertiary university hospital.
Fifty-one age matched subjects suffering from type 1 diabetes mellitus were selected for the study and evaluated for the following: salivary flow rate, number of decayed, missing and filled tooth in permanent dentition (DMF-T) and decayed, extracted, filled tooth index in the deciduous dentition (def-t); visible plaque index (VPI) and gingival bleeding index (GBI). STATISTICS AND ANALYSIS: The t test was utilized when the variables showed normal distribution. The Mann-Whitney test was utilized for comparing non-normal variables. Kolmorgorov-Smirnov test was used to assess the normality assumption. The differences were considered significant when P < 0.05.
The age and gender distribution of patients and controls was 11.3 ± 3.4 years (56% males) and 11.9 ± 3.4 years (37% males). The mean glycated hemoglobin value in the diabetics was 9.7 ± 1.9%. Salivary flow rate was lower in the diabetic patients as compared to controls (P = 0.02). No differences were found in the DMF-T/def-t indices of diabetic and non-diabetic patients (P = 0.43/0.14). VPI was similar in both the groups (P = 0.15). GBI was higher in the diabetics (8.1 vs. 5.18; P = 0.11). There were no differences in the dental caries experience and dental plaque in the two groups.
The lower salivary flow rate in diabetics could have been related to their higher GBI. The higher GBI in the diabetics is a matter of concern in the diabetics and is a sign for higher chances of developing periodontal problems.
尽管1型糖尿病（T1DM）对口腔健康有重大影响，但其与龋齿的关联尚不清楚。
本研究的目的是评估巴西1型糖尿病青少年的唾液流速和龋齿情况。
在一家三级大学医院进行了一项横断面研究。
选择51名年龄匹配的1型糖尿病患者进行研究，并对以下指标进行评估：唾液流速、恒牙列中龋失补牙数（DMF-T）和乳牙列中龋拔补牙指数（def-t）；可见菌斑指数（VPI）和牙龈出血指数（GBI）。统计与分析：当变量呈正态分布时使用t检验。使用曼-惠特尼检验比较非正态变量。使用柯尔莫哥洛夫-斯米尔诺夫检验评估正态性假设。当P<0.05时，差异被认为具有统计学意义。
患者和对照组的年龄和性别分布分别为11.3±3.4岁（男性占56%）和11.9±3.4岁（男性占37%）。糖尿病患者的糖化血红蛋白平均值为9.7±1.9%。与对照组相比，糖尿病患者的唾液流速较低（P = 0.02）。糖尿病患者和非糖尿病患者的DMF-T/def-t指数没有差异（P = 0.43/0.14）。两组的VPI相似（P = 0.15）。糖尿病患者的GBI较高（8.1对5.18；P = 0.11）。两组在龋齿经历和牙菌斑方面没有差异。
糖尿病患者较低的唾液流速可能与其较高的GBI有关。糖尿病患者较高的GBI值得关注，这表明患牙周问题的可能性更高。
