宫内暴露于阿片类药物后,对儿童的定期健康检查的坚持情况。

Well-Child Care Adherence After Intrauterine Opioid Exposure.

机构信息

Departments of Pediatrics and

Departments of Pediatrics and.

出版信息

Pediatrics. 2020 Feb;145(2). doi: 10.1542/peds.2019-1275. Epub 2020 Jan 2.

Abstract

BACKGROUND AND OBJECTIVES

For children with intrauterine opioid exposure (IOE), well-child care (WCC) provides an important opportunity to address medical, developmental, and psychosocial needs. We evaluated WCC adherence for this population.

METHODS

In this retrospective cohort study, we used PEDSnet data from a pediatric primary care network spanning 3 states from 2011 to 2016. IOE was ascertained by using physician diagnosis codes. WCC adherence in the first year was defined as a postnatal or 1-month visit and completed 2-, 4-, 6-, 9-, and 12-month visits. WCC adherence in the second year was defined as completed 15- and 18-month visits. Gaps in WCC, defined as ≥2 missed consecutive WCC visits, were also evaluated. We used multivariable regression to test the independent effect of IOE status.

RESULTS

Among 11 334 children, 236 (2.1%) had a diagnosis of IOE. Children with IOE had a median of 6 WCC visits (interquartile range 5-7), vs 8 (interquartile range 6-8) among children who were not exposed ( < .001). IOE was associated with decreased WCC adherence over the first and second years of life (adjusted relative risk 0.54 [ < .001] and 0.74 [ < .001]). WCC gaps were more likely in this population (adjusted relative risk 1.43; < .001). There were no significant adjusted differences in nonroutine primary care visits, immunizations by age 2, or lead screening.

CONCLUSIONS

Children <2 years of age with IOE are less likely to adhere to recommended WCC, despite receiving on-time immunizations and lead screening. Further research should be focused on the role of WCC visits to support the complex needs of this population.

摘要

背景和目的

对于宫内接触阿片类药物(IOE)的儿童,常规儿童保健(WCC)提供了一个解决医疗、发育和社会心理需求的重要机会。我们评估了这一人群的 WCC 依从性。

方法

在这项回顾性队列研究中,我们使用了 2011 年至 2016 年跨越三个州的儿科初级保健网络的 PEDSnet 数据。通过医生诊断代码确定 IOE。第一年的 WCC 依从性定义为产后或 1 个月就诊,完成 2、4、6、9 和 12 个月就诊。第二年的 WCC 依从性定义为完成 15 个月和 18 个月就诊。还评估了 WCC 的差距,定义为连续错过≥2 次 WCC 就诊。我们使用多变量回归来检验 IOE 状态的独立影响。

结果

在 11334 名儿童中,有 236 名(2.1%)被诊断为 IOE。与未接触 IOE 的儿童(中位数 8 次就诊,四分位距 6-8)相比,IOE 儿童的 WCC 就诊次数中位数为 6 次就诊(四分位距 5-7)(<0.001)。IOE 与生命的第一年和第二年 WCC 依从性下降有关(调整后的相对风险分别为 0.54[<0.001]和 0.74[<0.001])。在这一人群中,WCC 差距更有可能(调整后的相对风险 1.43;<0.001)。常规初级保健就诊、2 岁前免疫接种和铅筛查方面没有显著调整后的差异。

结论

尽管按时进行了免疫接种和铅筛查,但年龄<2 岁的宫内接触阿片类药物的儿童不太可能遵守推荐的 WCC。应进一步研究 WCC 就诊在满足这一人群复杂需求中的作用。

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