Fahey Jenifer O
J Midwifery Womens Health. 2008 May-Jun;53(3):227-235. doi: 10.1016/j.jmwh.2008.01.001.
Intra-amniotic infection (IAI), or chorioamnionitis, complicates up to 10% of all pregnancies and up to 2% of labors at term. There is a significant risk of complications for the mother and the neonate following IAI, including sepsis and pneumonia. In addition, there is a correlation between IAI and premature rupture of membranes, preterm premature rupture of membranes, preterm labor, and preterm birth. Research in the last decade has also revealed a complex and significant association between IAI and cerebral palsy and other central nervous system damage in both the preterm and term fetus. Timely diagnosis and treatment of IAI can significantly reduce the risk of both maternal and neonatal complications.
羊膜腔内感染（IAI），即绒毛膜羊膜炎，在所有妊娠中发生率高达10%，足月分娩中发生率高达2%。IAI发生后，母亲和新生儿出现并发症的风险很高，包括败血症和肺炎。此外，IAI与胎膜早破、未足月胎膜早破、早产和早产之间存在关联。过去十年的研究还揭示了IAI与早产和足月胎儿的脑瘫及其他中枢神经系统损伤之间存在复杂且显著的关联。及时诊断和治疗IAI可显著降低母婴并发症的风险。
