Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, School of Medicine, University of Alabama at Birmingham, 619 19th South, Birmingham, AL 3524, USA.
Clin Perinatol. 2010 Jun;37(2):339-54. doi: 10.1016/j.clp.2010.02.003.
Chorioamnionitis is a common complication of pregnancy associated with significant maternal, perinatal, and long-term adverse outcomes. Adverse maternal outcomes include postpartum infections and sepsis whereas adverse infant outcomes include stillbirth, premature birth, neonatal sepsis, chronic lung disease, and brain injury leading to cerebral palsy and other neurodevelopmental disabilities. Research in the past 2 decades has expanded understanding of the mechanistic links between intra-amniotic infection and preterm delivery as well as morbidities of preterm and term infants. Recent and ongoing clinical research into better methods for diagnosing, treating, and preventing chorioamnionitis is likely to have a substantial impact on short and long-term outcomes in the neonate.
绒毛膜羊膜炎是一种常见的妊娠并发症，与母体、围产期和长期不良后果密切相关。不良的母体后果包括产后感染和败血症，而不良的婴儿后果包括死产、早产、新生儿败血症、慢性肺部疾病和脑损伤，导致脑瘫和其他神经发育障碍。过去 20 年的研究扩大了对羊膜内感染与早产以及早产儿和足月儿发病率之间的机制联系的理解。最近和正在进行的关于更好的诊断、治疗和预防绒毛膜羊膜炎的临床研究可能会对新生儿的短期和长期结果产生重大影响。
