Ocheke A N, Ocheke I E, Agaba P A, Imadde G E, Silas O A, Ajetunmobi O I, Godwins Eche John, Ekere C, Sendeht A, Bitrus J, Agaba E I, Sagay A S
Department of Obstetrics and Gynaecology,Faculty of Medical Sciences, University of Jos, Jos, Nigeria.
Department of Paediatrics,Faculty of Medical Sciences, University of Jos, Jos, Nigeria.
J West Afr Coll Surg. 2016 Jul-Sep;6(3):1-14.
Clinical Chorioamnionitis contributes to maternal and neonatal morbidity and mortality but the effect of histological chorioamnionitis is sparse in our environment.
To determine the maternal and neonatal outcomes of histological chorioamnionitis amongst pregnant women and their babies.
Cross sectional longitudinal study.
Jos University Teaching Hospital (JUTH), Jos, Nigeria.
Parturients were interviewed and examined as well as had their placenta examined histologically for chorioamnionitis. They and their babies were followed up for 6 weeks after delivery to monitor for any complications that may arise.
A total of 148 parturients were enrolled from the labour ward of Jos University Teaching Hospital and of these 90 (60.8%) had histologic chorioamnionitis (HCA). As regards outcome, 9(10%) with histologic chorioamnionitis as well as 5(8.62%) of those without HCA had premature delivery. Low birth weight occurred in 12(13.33%) and 6(10.34 %) of those with HCA and without HCA respectively. In all, 1(1.47%) and 1(2.56%) of women with HCA and without HCA correspondingly had neonatal sepsis. Puerperal sepsis occurred in 2(2.94%) of those with HCA and 2(5.13%) of those without HCA.
Our study has demonstrated that histological chorioamnionitis had no adverse maternal or neonatal effect. There is the need for more studies investigating the cause and the implication of histological chorioamnionitis.
临床绒毛膜羊膜炎会导致孕产妇和新生儿发病及死亡,但在我们所处的环境中,组织学绒毛膜羊膜炎的影响却鲜有研究。
确定孕妇及其婴儿中组织学绒毛膜羊膜炎的孕产妇和新生儿结局。
横断面纵向研究。
尼日利亚乔斯市乔斯大学教学医院(JUTH)。
对产妇进行访谈和检查,并对其胎盘进行组织学检查以确定是否存在绒毛膜羊膜炎。分娩后对她们及其婴儿进行为期6周的随访,以监测可能出现的任何并发症。
从乔斯大学教学医院的产房共招募了148名产妇,其中90名(60.8%)患有组织学绒毛膜羊膜炎(HCA)。在结局方面,9名(10%)患有组织学绒毛膜羊膜炎的产妇以及5名(8.62%)未患HCA的产妇发生了早产。HCA组和非HCA组分别有12名(13.33%)和6名(10.34%)出现低出生体重。总体而言,HCA组和非HCA组分别有1名(1.47%)和1名(2.56%)产妇的新生儿发生败血症。HCA组和非HCA组分别有2名(2.94%)和2名(5.13%)产妇发生产褥期败血症。
我们的研究表明,组织学绒毛膜羊膜炎对孕产妇或新生儿没有不良影响。有必要开展更多研究来调查组织学绒毛膜羊膜炎的病因及其影响。