Mason W Alex, Hitchings Julia E, Spoth Richard L
Social Development Research Group, University of Washington, 9725 3rd Avenue NE, Suite 401, Seattle, WA 98115, USA.
Drug Alcohol Depend. 2008 Aug 1;96(3):233-48. doi: 10.1016/j.drugalcdep.2008.03.012. Epub 2008 May 2.
Conduct problems are strong positive predictors of substance use and problem substance use among teens, whereas predictive associations of depressed mood with these outcomes are mixed. Conduct problems and depressed mood often co-occur, and such co-occurrence may heighten risk for negative outcomes. Thus, this study examined the interaction of conduct problems and depressed mood at age 11 in relation to substance use and problem use at age 18, and possible mediation through peer substance use at age 16. Analyses of multirater longitudinal data collected from 429 rural youths (222 girls) and their families were conducted using a methodology for testing latent variable interactions. The link between the conduct problems x depressed mood interaction and adolescent substance use was negative and statistically significant. Unexpectedly, positive associations of conduct problems with substance use were stronger at lower levels of depressed mood. A significant negative interaction in relation to peer substance use also was observed, and the estimated indirect effect of the interaction on adolescent use through peer use as a mediator was statistically significant. Findings illustrate the complexity of multiproblem youth.
行为问题是青少年物质使用和问题物质使用的有力正向预测因素，而抑郁情绪与这些结果之间的预测关联则较为复杂。行为问题和抑郁情绪常常同时出现，这种共现可能会增加负面结果的风险。因此，本研究考察了11岁时行为问题与抑郁情绪的交互作用与18岁时物质使用及问题使用之间的关系，以及16岁时同伴物质使用可能起到的中介作用。使用一种用于检验潜在变量交互作用的方法，对从429名农村青少年（222名女孩）及其家庭收集的多评估者纵向数据进行了分析。行为问题×抑郁情绪的交互作用与青少年物质使用之间的联系呈负相关且具有统计学意义。出乎意料的是，在抑郁情绪较低水平时，行为问题与物质使用的正相关更强。在同伴物质使用方面也观察到显著的负向交互作用，并且交互作用通过同伴使用作为中介对青少年使用的估计间接效应具有统计学意义。研究结果说明了多问题青少年的复杂性。
